Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24739167 | 0.84 | NR1H2 (0.40) | — | |
| SCHEMBL19198461 | 0.81 | MMP2 (0.40) | MMP2ANPEPATM | |
| SCHEMBL16349661 | 0.77 | ATM (0.40) | MMP2ANPEPATM | |
| SCHEMBL16316489 | 0.77 | ATM (0.40) | MMP2ANPEPATM | |
| SCHEMBL16300658 | 0.77 | ATM (0.40) | MMP2ANPEPATM | |
| SCHEMBL14596219 | 0.75 | NR1H2 (0.30) | — | |
| SCHEMBL22372628 | 0.75 | — | — | |
| SCHEMBL13337538 | 0.75 | — | — | |
| SCHEMBL13684693 | 0.75 | — | — | |
| SCHEMBL8262943 | 0.72 | NR1H2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592316-B2 | Peptides as NS3-serine protease inhibitors of hepatitis C virus | SCHERING CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |
| EP-1939213-A1 | Novel compounds as inhibitors of hepatitis C virus NS3 serine protease | SCHERING CORPORATION (US) | 2008-07-02 | — | — | EP | disclosed |