Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20995893 | 0.80 | PPM1B (0.52) | PPM1BPTPN1PPP1CCCYP2C19CHRNB2 | |
| SCHEMBL2158225 | 0.79 | TRPA1 (0.41) | TRPA1TRPM8SLC6A4 | |
| SCHEMBL27013380 | 0.73 | CHRM2 (0.40) | TRPA1TRPM8SLC6A4 | |
| SCHEMBL16948282 | 0.73 | CHRNB2 (0.41) | PPM1BPTPN1PPP1CCCHRNB2CHRNA4 | |
| SCHEMBL30933026 | 0.73 | PPM1B (0.39) | PPM1BPTPN1PPP1CCCYP2C19CHRNB2 | |
| SCHEMBL28287653 | 0.72 | PPM1B (0.60) | PPM1BPTPN1PPP1CCCYP2C19 | |
| SCHEMBL15635564 | 0.72 | CHRM2 (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL24240089 | 0.72 | — | — | |
| SCHEMBL22100978 | 0.72 | — | — | |
| SCHEMBL19190722 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7731957-B1 | High-activity mutants of butyrylcholinesterase for cocaine hydrolysis and method of generating the same | UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) | 2010-06-08 | — | — | US | disclosed |