Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TERF2 | Q15554 | 3/20 | 0.37 |
| ▸ | XIAP | P98170 | 2/20 | 0.37 |
| ▸ | BIRC3 | Q13489 | 2/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 8/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8291443 | 0.93 | F2 (0.43) | F2F10PRSS1GAATERF2 | |
| SCHEMBL8291503 | 0.88 | F2 (0.41) | F2F10PRSS1GAATERF2 | |
| SCHEMBL16349820 | 0.85 | GAA (0.35) | F2F10PRSS1GAA | |
| SCHEMBL1655875 | 0.82 | BIRC3 (0.38) | F2F10PRSS1GAATERF2 | |
| SCHEMBL16349581 | 0.81 | GAA (0.35) | F2F10PRSS1GAA | |
| SCHEMBL16349734 | 0.81 | GAA (0.35) | F2F10PRSS1GAA | |
| SCHEMBL16315715 | 0.81 | GAA (0.35) | F2F10PRSS1GAA | |
| SCHEMBL8290665 | 0.79 | GAA (0.42) | GAATERF2HDAC4HDAC1 | |
| SCHEMBL13685693 | 0.79 | F2 (0.37) | F2F10PRSS1GAA | |
| SCHEMBL8249283 | 0.79 | TERF2 (0.35) | F2F10PRSS1TERF2XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7592419-B2 | Macrocyclic inhibitors of hepatitis C virus NS3-serine protease | SCHERING CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |