Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3166464 | 0.68 | PTPN1 (0.36) | MEN1KMT2A | |
| SCHEMBL24967885 | 0.65 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL14614470 | 0.64 | SCN1A (0.49) | MEN1KMT2ALMNA | |
| SCHEMBL12118788 | 0.62 | TSHR (0.40) | MEN1KMT2AALDH1A1 | |
| SCHEMBL567667 | 0.62 | TSHR (0.40) | MEN1KMT2AALDH1A1 | |
| SCHEMBL1969195 | 0.62 | MEN1 (0.37) | MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL10799911 | 0.62 | SLC6A3 (0.37) | MEN1KMT2ALMNANPSR1 | |
| SCHEMBL8763246 | 0.61 | MEN1 (0.44) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL10807859 | 0.60 | SLC6A3 (0.36) | MEN1KMT2ALMNANPSR1 | |
| SCHEMBL9354384 | 0.60 | MEN1 (0.41) | MEN1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718781-B2 | Hydroxypyridonate and hydroxypyrimidinone chelating agents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-05-18 | — | — | US | disclosed |