SCHEMBL16351203

CCOCCNC(=O)CCN(CCC(=O)NCCOCC)C(=O)CNC(=O)CCN(CCC(=O)NCC(=O)N(CCC(=O)NCCOCCOCC)CCC(=O)NCCOCCOCC(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)O)[C@H](C)O)C(=O)CNC(=O)CSC(C)=O

nearest known ligand 0.48

Predicted protein targets (top 6)

	gene	UniProt	supporting neighbours	confidence
▸	RAMP3	O60896	15/20	0.48

▸	CALCR	P30988	15/20	0.48

▸	APLNR	P35414	1/20	0.46

▸	IL23R	Q5VWK5	1/20	0.44

▸	NMUR2	Q9GZQ4	2/20	0.41

▸	NMUR1	Q9HB89	2/20	0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL16340730	0.91	RAMP3 (0.50)	RAMP3CALCRAPLNRIL23RNMUR2
SCHEMBL16340628	0.91	APLNR (0.42)	RAMP3CALCRAPLNRIL23RNMUR2
SCHEMBL12314904	0.86	APLNR (0.38)	RAMP3CALCRAPLNR
SCHEMBL12339085	0.84	RAMP3 (0.46)	RAMP3CALCRIL23R
SCHEMBL16351204	0.84	RAMP3 (0.46)	RAMP3CALCRIL23R
SCHEMBL12337845	0.84	RAMP3 (0.46)	RAMP3CALCRAPLNRIL23RNMUR2
SCHEMBL12337799	0.83	RAMP3 (0.46)	RAMP3CALCRAPLNRIL23RNMUR2
SCHEMBL12314876	0.80	RAMP3 (0.47)	RAMP3CALCRIL23R
SCHEMBL13084645	0.80	RAMP3 (0.47)	RAMP3CALCRIL23R
SCHEMBL12314880	0.80	RAMP3 (0.47)	RAMP3CALCRIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-8263739-B2	also targeting tumor cells that express vascular endothelial growth factor neuropilin-1 receptor; radiotherapy; radiopharmaceuticals; treating angiogenesis	BRACCO SUISSE SA (CH)	2012-09-11	—	—	US	disclosed