SCHEMBL16351395

SCHEMBL16351395

OCC1O[C@@H](OP(O)(O)=S)C(O)C(O)C1O

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ GAA P10253 1/20 0.45
▸ TYR P14679 1/20 0.45
▸ MAPT P10636 1/20 0.45
▸ MEN1 O00255 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ LGALS1 P09382 2/20 0.41
▸ LGALS3 P17931 2/20 0.41
▸ LGALS9 O00182 1/20 0.41
▸ LGALS8 O00214 1/20 0.41
▸ POLB P06746 1/20 0.41
▸ PTPN1 P18031 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL104855 0.81 L3MBTL1 (0.46) L3MBTL1GAATYRMAPT
SCHEMBL1521155 0.81 L3MBTL1 (0.46) L3MBTL1GAATYRMAPT
SCHEMBL284741 0.81 L3MBTL1 (0.46) L3MBTL1GAATYRMAPT
SCHEMBL7549072 0.81 L3MBTL1 (0.46) L3MBTL1GAATYRMAPT
SCHEMBL9208454 0.81 L3MBTL1 (0.46) L3MBTL1GAATYRMAPT
SCHEMBL24021536 0.81 L3MBTL1 (0.46) L3MBTL1GAATYRMAPT
SCHEMBL7550356 0.81 L3MBTL1 (0.46) L3MBTL1GAATYRMAPT
SCHEMBL7549080 0.81 L3MBTL1 (0.46) L3MBTL1GAATYRMAPT
SCHEMBL1521609 0.81 L3MBTL1 (0.46) L3MBTL1GAATYRMAPT
SCHEMBL7545194 0.81 L3MBTL1 (0.46) L3MBTL1GAATYRMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140378408-A1 NUCLEOSIDE 5'-PHOSPHOROTHIOATE ANALOGUES AND USES THEREOF BAR ILAN UNIVERSITY AN ISRAELI UNIVERSITY (IL) 2014-12-25 — — US disclosed
US-20140378408-A1 NUCLEOSIDE 5'-PHOSPHOROTHIOATE ANALOGUES AND USES THEREOF BAR ILAN UNIVERSITY AN ISRAELI UNIVERSITY (IL) 2014-12-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140378408-A1 NUCLEOSIDE 5'-PHOSPHOROTHIOATE ANALOGUES AND USES THEREOF CCL2, NUDT1, CXCL12 L3MBTL1 3412/4885GAA 3236/4885TYR 3360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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