Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 5/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 4/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 4/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | HNF4A | P41235 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 2/20 | 0.41 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16320836 | 0.87 | MCL1 (0.70) | MCL1TDP1EGFR | |
| SCHEMBL16351978 | 0.83 | TSHR (0.51) | MCL1TDP1ALDH1A1CYP3A4TSHR | |
| SCHEMBL18621853 | 0.82 | ESR1 (0.49) | TDP1ALDH1A1CYP3A4DHODH | |
| SCHEMBL16351942 | 0.81 | L3MBTL1 (0.46) | TDP1L3MBTL1DHODH | |
| SCHEMBL16351980 | 0.81 | NPC1 (0.47) | TDP1EGFRCA12CA1CA2 | |
| SCHEMBL28362416 | 0.81 | TDP1 (0.67) | MCL1TDP1EGFRACMSDDHFR | |
| SCHEMBL17488407 | 0.79 | ALDH1A1 (0.44) | TDP1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL5695898 | 0.78 | L3MBTL1 (0.57) | TDP1EGFRCA12CA1CA2 | |
| SCHEMBL5695937 | 0.78 | TDP1 (0.67) | TDP1EGFRCA12CA1CA2 | |
| SCHEMBL16351979 | 0.77 | ESR1 (0.51) | TDP1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567526-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-02-14 | — | — | US | disclosed |
| US-20140375943-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2014-12-25 | — | — | US | disclosed |