Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16321119 | 0.87 | MCL1 (0.56) | TSHRTDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL16351975 | 0.84 | TDP1 (0.43) | TSHRTDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL16351973 | 0.83 | MCL1 (0.51) | TSHRTDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL16351976 | 0.79 | TDP1 (0.46) | TSHRTDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL16016786 | 0.77 | ALDH1A1 (0.67) | TSHRTDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL18621853 | 0.77 | ESR1 (0.49) | TDP1ALDH1A1CYP3A4TP53DHODH | |
| SCHEMBL16351942 | 0.77 | L3MBTL1 (0.46) | TDP1L3MBTL1TP53DHODHLMNA | |
| SCHEMBL16351849 | 0.74 | TSHR (0.56) | TSHRTDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL16351839 | 0.74 | TSHR (0.56) | TSHRTDP1ALDH1A1L3MBTL1CYP3A4 | |
| SCHEMBL17488407 | 0.74 | ALDH1A1 (0.44) | TSHRTDP1ALDH1A1L3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9567526-B2 | Polymerizable compounds and the use thereof in liquid-crystal displays | MERCK PATENT GMBH (DE) | 2017-02-14 | — | — | US | disclosed |
| US-20140375943-A1 | POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2014-12-25 | — | — | US | disclosed |