Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | UGT2B7 | P16662 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5918893 | 0.81 | PPARD (0.50) | PPARDTSHRTP53TDP1UGT2B7 | |
| SCHEMBL10590815 | 0.80 | PPARD (0.54) | PPARDTSHRTP53TDP1UGT2B7 | |
| SCHEMBL16062694 | 0.80 | PPARD (0.54) | PPARDTSHRTP53TDP1UGT2B7 | |
| SCHEMBL3313657 | 0.74 | PPARD (0.70) | PPARDTSHRTP53TDP1MEN1 | |
| SCHEMBL559843 | 0.73 | PPARD (0.47) | PPARDTSHRTP53TDP1UGT2B7 | |
| SCHEMBL5329595 | 0.72 | PPARD (0.50) | PPARDTSHRTP53TDP1UGT2B7 | |
| SCHEMBL28029802 | 0.72 | TSHR (0.41) | PPARDTSHRTP53TDP1MEN1 | |
| SCHEMBL10037944 | 0.72 | PPARD (0.50) | PPARDTSHRTP53TDP1UGT2B7 | |
| SCHEMBL508153 | 0.71 | TSHR (0.50) | PPARDTSHRTP53TDP1LMNA | |
| Water SCHEMBL6830152 | 0.71 | PPARD (0.48) | PPARDTSHRTP53TDP1UGT2B7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9593136-B2 | Compounds for inhibiting 1-deoxy-D-xylulose-5-phosphate reductoisomerase | THE GEORGE WASHINGTON UNIVERSITY (US) | 2017-03-14 | — | — | US | disclosed |
| US-20140378418-A1 | COMPOUNDS FOR INHIBITING 1-DEOXY-D-XYLULOSE-5-PHOSPHATE REDUCTOISOMERASE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2014-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378418-A1 | COMPOUNDS FOR INHIBITING 1-DEOXY-D-XYLULOSE-5-PHOSPHATE REDUCTOISOMERASE | DCXR, G6PD, GRHPR | PPARD 2765/4885TSHR 1505/4885TP53 4649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.