SCHEMBL559843

SCHEMBL559843

CCOP(=O)(CCC(C)C=O)OCC

nearest known ligand 0.47

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 2/20 0.47
TSHR P16473 2/20 0.43
UGT2B7 P16662 2/20 0.34
TP53 P04637 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
AOX1 Q06278 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2455708 0.89 PPARD (0.44) PPARDTSHRTP53TDP1AOX1
SCHEMBL11508933 0.79 TSHR (0.46) PPARDTSHRUGT2B7TP53TDP1
SCHEMBL10590815 0.79 PPARD (0.54) PPARDTSHRUGT2B7TP53TDP1
SCHEMBL16062694 0.79 PPARD (0.54) PPARDTSHRUGT2B7TP53TDP1
SCHEMBL16352174 0.73 PPARD (0.48) PPARDTSHRUGT2B7TP53TDP1
SCHEMBL28358625 0.73 PPARD (0.44) PPARDTSHRUGT2B7TP53TDP1
SCHEMBL3313657 0.72 PPARD (0.70) PPARDTSHRTP53TDP1
SCHEMBL5918893 0.71 PPARD (0.50) PPARDTSHRUGT2B7TP53TDP1
SCHEMBL5329595 0.71 PPARD (0.50) PPARDTSHRUGT2B7TP53TDP1
SCHEMBL10037944 0.71 PPARD (0.50) PPARDTSHRUGT2B7TP53TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9110069-B2 Luminescent compounds SETA BIOMEDICALS, LLC (US) 2015-08-18 US disclosed
US-20140086844-A1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS, LLC (US) 2014-03-27 US disclosed
US-8552027-B2 Luminescent compounds SETA BIOMEDICALS, LLC (US) 2013-10-08 US disclosed
US-20120035346-A1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS, LLC 2012-02-09 US disclosed
WO-2010083471-A1 LUMINESCENT COMPOUNDS SETA BIOMEDICALS, LLC (US) 2010-07-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140086844-A1 LUMINESCENT COMPOUNDS PHOSPHO1, PGLS, PFAS PPARD 1479/4885TSHR 4592/4885UGT2B7 3144/4885
US-20120035346-A1 LUMINESCENT COMPOUNDS PHOSPHO1, PGLS, PFAS PPARD 1374/4885TSHR 4660/4885UGT2B7 3134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.