SCHEMBL163535

SCHEMBL163535

NCC(O)C(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.56
EPHX2 P34913 1/20 0.49
FABP5 Q01469 3/20 0.48
FABP7 O15540 2/20 0.48
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
HTR2A P28223 1/20 0.46
CASP3 P42574 2/20 0.41
MDM4 O15151 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL31454960 0.92 KMT2A (0.49) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL4970478 0.88 KMT2A (0.53) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL17744918 0.85 KMT2A (0.51) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL1436990 0.84 KMT2A (0.56) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL1504724 0.83 KMT2A (0.49) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL27873417 0.83 KMT2A (0.55) KMT2AEPHX2FABP5FABP7CA1
Hydrochloric Acid SCHEMBL2174098 0.83 KMT2A (0.55) KMT2AEPHX2FABP5FABP7CA1
Bromide SCHEMBL15671138 0.83 KMT2A (0.55) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL1162471 0.83 KMT2A (0.55) KMT2AEPHX2FABP5FABP7CA1
SCHEMBL3683870 0.81 KMT2A (0.52) KMT2AEPHX2FABP5FABP7CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12497460-B2 Anti-MSR1 antibodies and methods of use thereof REGENERON PHARMACEUTICALS, INC. (US) 2025-12-16 US disclosed
US-20250064954-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2025-02-27 US disclosed
US-12156913-B2 Biodegradable liquogel and pH sensitive nanocarriers NORTH CAROLINA CENTRAL UNIVERSITY (US) 2024-12-03 US disclosed
CN-118955604-A Steroid compounds and antibody conjugates thereof 里珍纳龙药品有限公司 2024-11-15 CN disclosed
US-20240342299-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMA (US) 2024-10-17 US disclosed
US-12070506-B2 Steroids and antibody-conjugates thereof REGENERON PHARMACEUTICALS, INC. (US) 2024-08-27 US disclosed
CN-112004557-B Steroid compounds and antibody conjugates thereof 里珍纳龙药品有限公司 2024-07-30 CN disclosed
US-20230079407-A1 ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF REGENERON PHARMACEUTICALS, INC. 2023-03-16 US disclosed
US-11377502-B2 Anti-MSR1 antibodies and methods of use thereof REGENERON PHARMACEUTICALS, INC. (US) 2022-07-05 US disclosed
US-20210284655-A1 LIBRARIES OF HETEROARYL-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME CYCLENIUM PHARMA INC. (CA) 2021-09-16 US disclosed
EP-1871343-A2 MICELLE COMPOSITION OF POLYMER AND PASSENGER DRUG WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2008-01-02 EP disclosed
US-20060251710-A1 Micelle composition of polymer and passenger drug NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2006-11-09 US disclosed
WO-2006110862-A2 MICELLE COMPOSITION OF POLYMER AND PASSENGER DRUG WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2006-10-19 WO disclosed
US-7067620-B2 Antibacterial agents THERAVANCE, INC. (US) 2006-06-27 US disclosed
CN-1249081-C Glycopeptide derivatives or pharmaceutical compositions containing them ADVANCED MEDICINE INC (US) 2006-04-05 CN disclosed
US-20050171010-A1 NOVEL ANTIBACTERIAL AGENTS CUMBERLAND PHARMACEUTICALS INC. 2005-08-04 US disclosed
US-6518242-B1 Derivatives of glycopeptide antibacterial agents THERAVANCE, INC. 2003-02-11 US disclosed
CN-1315961-A Glycopeptide derivatives and pharmaceutical compositions containing same ADVANCED MEDICINE INC (US) 2001-10-03 CN disclosed
EP-1060189-A1 DERIVATIVES OF GLYCOPEPTIDE ANTIBACTERIAL AGENTS Advanced Medicine, Inc. (US) 2000-12-20 EP disclosed
WO-1999042476-A1 NOVEL ANTIBACTERIAL AGENTS ADVANCED MEDICINE, INC. (US) 1999-08-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240342299-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 KMT2A 4385/4885EPHX2 2214/4885FABP5 414/4885
US-12070506-B2 Steroids and antibody-conjugates thereof SERPINA6, NR3C1, NR3C2 KMT2A 4385/4885EPHX2 2214/4885FABP5 414/4885
US-20050171010-A1 NOVEL ANTIBACTERIAL AGENTS ENGASE, GALE, MGAM KMT2A 4630/4885EPHX2 2301/4885FABP5 632/4885
US-20230079407-A1 ANTI-MSR1 ANTIBODIES AND METHODS OF USE THEREOF CD47, MSR1, LDLR KMT2A 710/4885EPHX2 4662/4885FABP5 419/4885
US-20210284655-A1 LIBRARIES OF HETEROARYL-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME NCOA3, VDR, GRK3 KMT2A 3787/4885EPHX2 3147/4885FABP5 871/4885
US-20250064954-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 KMT2A 4385/4885EPHX2 2214/4885FABP5 414/4885
US-12497460-B2 Anti-MSR1 antibodies and methods of use thereof CD47, MSR1, LDLR KMT2A 710/4885EPHX2 4662/4885FABP5 419/4885
US-11377502-B2 Anti-MSR1 antibodies and methods of use thereof CD47, MSR1, LDLR KMT2A 710/4885EPHX2 4662/4885FABP5 419/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.