Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.46 |
| ▸ | FABP7 | O15540 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 2/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17744918 | 0.92 | KMT2A (0.51) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL1504724 | 0.89 | KMT2A (0.49) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL163535 | 0.88 | KMT2A (0.56) | KMT2AFABP5FABP7CA1CA2 | |
| Hydrochloric Acid SCHEMBL31758313 | 0.85 | KMT2A (0.53) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL1901193 | 0.85 | KMT2A (0.53) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL8815101 | 0.85 | KMT2A (0.45) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL14947096 | 0.84 | KMT2A (0.52) | KMT2AFABP5FABP7CA1CA2 | |
| Hydrochloric Acid SCHEMBL6366019 | 0.84 | KMT2A (0.52) | KMT2AFABP5FABP7CA1CA2 | |
| Bromide SCHEMBL16269651 | 0.84 | KMT2A (0.52) | KMT2AFABP5FABP7CA1CA2 | |
| SCHEMBL1940665 | 0.84 | KMT2A (0.52) | KMT2AFABP5FABP7CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210284655-A1 | LIBRARIES OF HETEROARYL-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CYCLENIUM PHARMA INC. (CA) | 2021-09-16 | — | — | US | disclosed |
| US-10981931-B2 | Libraries of heteroaryl-containing macrocyclic compounds and methods of making and using the same | CYCLENIUM PHARMA INC. (CA) | 2021-04-20 | — | — | US | disclosed |
| US-20200190083-A1 | LIBRARIES OF PYRIDINE-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CYCLENIUM PHARMA INC. (CA) | 2020-06-18 | — | — | US | disclosed |
| US-20200157116-A1 | LIBRARIES OF HETEROARYL-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CYCLENIUM PHARMA INC. (CA) | 2020-05-21 | — | — | US | disclosed |
| EP-3642399-A1 | LIBRARIES OF PYRIDINE-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | Cyclenium Pharma Inc. (CA) | 2020-04-29 | — | — | EP | disclosed |
| US-10407442-B2 | Libraries of heteroaryl-containing macrocyclic compounds and methods of making and using the same | CYCLENIUM PHARMA INC. (CA) | 2019-09-10 | — | — | US | disclosed |
| US-20190153620-A1 | LIBRARIES OF DIVERSE MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CYCLENIUM PHARMA INC. (CA) | 2019-05-23 | — | — | US | disclosed |
| EP-3458630-A1 | LIBRARIES OF DIVERSE MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | Cyclenium Pharma Inc. (CA) | 2019-03-27 | — | — | EP | disclosed |
| WO-2018232506-A1 | LIBRARIES OF PYRIDINE-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CYCLENIUM PHARMA INC. (CA) | 2018-12-27 | — | — | WO | disclosed |
| US-20180265521-A1 | LIBRARIES OF HETEROARYL-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CYCLENIUM PHARMA INC. (CA) | 2018-09-20 | — | — | US | disclosed |
| EP-3353341-A1 | LIBRARIES OF HETEROARYL-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | Cyclenium Pharma Inc. (CA) | 2018-08-01 | — | — | EP | disclosed |
| WO-2017197488-A1 | LIBRARIES OF DIVERSE MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CYCLENIUM PHARMA INC. (CA) | 2017-11-23 | — | — | WO | disclosed |
| WO-2017049383-A1 | LIBRARIES OF HETEROARYL-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CYCLENIUM PHARMA INC. (CA) | 2017-03-30 | — | — | WO | disclosed |
| EP-1934236-A1 | HETEROBIFUNCTIONAL PAN-SELECTIN INHIBITORS | GlycoMimetics, Inc. (US) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007028050-A1 | HETEROBIFUNCTIONAL PAN-SELECTIN INHIBITORS | GLYCOMIMETICS, INC. (US) | 2007-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200157116-A1 | LIBRARIES OF HETEROARYL-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | NCOA3, VDR, GRK3 | KMT2A 3787/4885FABP5 871/4885FABP7 158/4885 |
| US-20190153620-A1 | LIBRARIES OF DIVERSE MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | VDR, TRPM8, TRPM7 | KMT2A 4512/4885FABP5 857/4885FABP7 108/4885 |
| US-20210284655-A1 | LIBRARIES OF HETEROARYL-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | NCOA3, VDR, GRK3 | KMT2A 3787/4885FABP5 871/4885FABP7 158/4885 |
| US-10981931-B2 | Libraries of heteroaryl-containing macrocyclic compounds and methods of making and using the same | NCOA3, VDR, GRK3 | KMT2A 3787/4885FABP5 871/4885FABP7 158/4885 |
| US-20200190083-A1 | LIBRARIES OF PYRIDINE-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | VDR, TRPM8, TRPM7 | KMT2A 4027/4885FABP5 1410/4885FABP7 377/4885 |
| US-20180265521-A1 | LIBRARIES OF HETEROARYL-CONTAINING MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | NCOA3, VDR, GRK3 | KMT2A 3787/4885FABP5 871/4885FABP7 158/4885 |
| US-10407442-B2 | Libraries of heteroaryl-containing macrocyclic compounds and methods of making and using the same | NCOA3, VDR, GRK3 | KMT2A 3787/4885FABP5 871/4885FABP7 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.