Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNMT1 | P26358 | 6/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.52 |
| ▸ | TK1 | P04183 | 1/20 | 0.49 |
| ▸ | DNMT3B | Q9UBC3 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1635378 | 1.00 | DNMT1 (0.52) | DNMT1ADRB1TK1DNMT3BPOLB | |
| Ibacitabine SCHEMBL225403 | 0.91 | DNMT1 (0.63) | DNMT1ADRB1TK1DNMT3BFPR2 | |
| Ibacitabine SCHEMBL21423094 | 0.91 | DNMT1 (0.63) | DNMT1ADRB1TK1DNMT3BFPR2 | |
| Ibacitabine SCHEMBL225402 | 0.91 | DNMT1 (0.63) | DNMT1ADRB1TK1DNMT3BFPR2 | |
| Ibacitabine SCHEMBL13812993 | 0.91 | DNMT1 (0.63) | DNMT1ADRB1TK1DNMT3BFPR2 | |
| Ibacitabine SCHEMBL887475 | 0.91 | DNMT1 (0.63) | DNMT1ADRB1TK1DNMT3BFPR2 | |
| Ibacitabine SCHEMBL5981937 | 0.91 | DNMT1 (0.63) | DNMT1ADRB1TK1DNMT3BFPR2 | |
| Ibacitabine SCHEMBL244921 | 0.91 | DNMT1 (0.63) | DNMT1ADRB1TK1DNMT3BFPR2 | |
| Ibacitabine SCHEMBL5981939 | 0.91 | DNMT1 (0.63) | DNMT1ADRB1TK1DNMT3BFPR2 | |
| SCHEMBL2611634 | 0.90 | DNMT1 (0.50) | DNMT1ADRB1TK1DNMT3BPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4093715-A | 5-Iodo-5'-amino-2',5'-dideoxycytidine and the pharmaceutically acceptable salts thereof | RESEARCH CORPORATION (US) | 1978-06-06 | — | — | US | claimed |
| US-20110265195-A1 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2011-10-27 | — | — | US | disclosed |
| US-7932066-B2 | Unique associated kaposi's sarcoma virus sequences and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2011-04-26 | — | — | US | disclosed |
| US-20090022748-A1 | Unique associated Kaposi's sarcoma virus sequences and uses thereof | CHANG YUAN | 2009-01-22 | — | — | US | disclosed |
| US-6348586-B1 | NUCLEOTIDE SEQUENCE OF HERPES VIRUS; DIAGNOSIS; VACCINES; VIRICIDES; ANTISENSE AGENTS; TRIPLEX OLIGONUCLEOTIDES; | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2002-02-19 | — | — | US | disclosed |
| US-6183751-B1 | VACCINES; DIAGNOSIS; OPEN READING FRAME; GENETIC ENGINEERING | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2001-02-06 | — | — | US | disclosed |
| US-6150093-A | NUCLEOTIDE SEQUENCES PREFERENTIAL FOR HERPES VIRUS ASSOCIATED WITH A CANCER; FOR TREATMENT, DIAGNOSIS AND DETECTION OF AQUIRED IMMUNODEFICIENCY SYNDROME RELATED CANCER | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2000-11-21 | — | — | US | disclosed |
| US-6093550-A | DIAGNOSING KAPOSI'S SARCOMA(KS) ASSOCIATED HERPESVIRUS INFECTION BY CONTACTING A SAMPLE WITH A KS ASSOCIATED HERPESVIRUS ANTIGEN, DETERMINING THE LEVEL OF KS ASSOCIATED HERPESVIRUS ANTIBODY BOUND TO THE ANTIGEN; IMMUNOASSAY KITS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2000-07-25 | — | — | US | disclosed |
| US-5948676-A | Immediate early protein from Kaposi's sarcoma-associated herpesvirus, DNA encoding same and uses thereof | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1999-09-07 | — | — | US | disclosed |
| US-5863787-A | DNA MOLECULES WHICH ENCODES GLYCOPROTEIN B AND ANTISENSE AND TRIPLEX OLIGONUCLEOTIDES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1999-01-26 | — | — | US | disclosed |
| US-5801042-A | DNA AND NUCLEIC ACIDS FOR HERPESVIRUS GLYCOPROTEIN H, PLASMIDS AND GENOMES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1998-09-01 | — | — | US | disclosed |
| EP-0726708-A1 | VIRUS ASSOCIATED MULTIPLE SCLEROSIS: TREATMENTS, PREVENTION AND DIAGNOSIS THEREOF | PATHOGENESIS CORPORATION (US) | 1996-08-21 | — | — | EP | disclosed |
| WO-1996006159-A1 | UNIQUE ASSOCIATED KAPOSI'S SARCOMA VIRUS SEQUENCES AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 1996-02-29 | — | — | WO | disclosed |
| WO-1995012313-A1 | VIRUS ASSOCIATED MULTIPLE SCLEROSIS: TREATMENTS, PREVENTION AND DIAGNOSIS THEREOF | PATHOGENESIS CORPORATION (US) | 1995-05-11 | — | — | WO | disclosed |
| US-5213972-A | Production of thymidine and deoxyuridine, intermediates for AZT | CHEMGEN CORPORATION (US) | 1993-05-25 | — | — | US | disclosed |
| WO-1992020816-A1 | DETERMINATION OF PRODRUGS METABOLIZABLE BY THE LIVER AND THERAPEUTIC USE THEREOF | YALE UNIVERSITY (US) | 1992-11-26 | — | — | WO | disclosed |
| US-4710492-A | MURINE LEUKEMIA, SARCOMA AND AIDS VIRUSES | YALE UNIVERSITY (US) | 1987-12-01 | — | — | US | disclosed |
| US-4093715-A | 5-Iodo-5'-amino-2',5'-dideoxycytidine and the pharmaceutically acceptable salts thereof | RESEARCH CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |
| US-4093715-A | 5-Iodo-5'-amino-2',5'-dideoxycytidine and the pharmaceutically acceptable salts thereof | RESEARCH CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |
| US-4093715-A | 5-Iodo-5'-amino-2',5'-dideoxycytidine and the pharmaceutically acceptable salts thereof | RESEARCH CORPORATION (US) | 1978-06-06 | — | — | US | disclosed |