Ibacitabine

Ibacitabine

SCHEMBL244921

Nc1nc(=O)n(C2CC(O)C(CO)O2)cc1I

nearest known ligand 0.63

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 6/20 0.63
ADRB1 P08588 1/20 0.63
TK1 P04183 2/20 0.60
DNMT3B Q9UBC3 2/20 0.54
LMNA P02545 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
PNP P00491 1/20 0.49
TP53 P04637 1/20 0.49
HTT P42858 1/20 0.49
PDE4D Q08499 1/20 0.49
PDE3A Q14432 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
FPR2 P25090 1/20 0.48
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
TSHR P16473 1/20 0.47
BLM P54132 1/20 0.47
PMP22 Q01453 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ibacitabine SCHEMBL5981937 1.00 DNMT1 (0.63) DNMT1ADRB1TK1DNMT3BLMNA
Ibacitabine SCHEMBL21423094 1.00 DNMT1 (0.63) DNMT1ADRB1TK1DNMT3BLMNA
Ibacitabine SCHEMBL225403 1.00 DNMT1 (0.63) DNMT1ADRB1TK1DNMT3BLMNA
Ibacitabine SCHEMBL5981939 1.00 DNMT1 (0.63) DNMT1ADRB1TK1DNMT3BLMNA
Ibacitabine SCHEMBL13812993 1.00 DNMT1 (0.63) DNMT1ADRB1TK1DNMT3BLMNA
Ibacitabine SCHEMBL887475 1.00 DNMT1 (0.63) DNMT1ADRB1TK1DNMT3BLMNA
Ibacitabine SCHEMBL225402 1.00 DNMT1 (0.63) DNMT1ADRB1TK1DNMT3BLMNA
SCHEMBL1635378 0.91 DNMT1 (0.52) DNMT1ADRB1TK1DNMT3BFPR2
SCHEMBL1635376 0.91 DNMT1 (0.52) DNMT1ADRB1TK1DNMT3BFPR2
Ibacitabine SCHEMBL9710365 0.91 DNMT1 (0.54) DNMT1ADRB1TK1DNMT3BLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4401 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139860-A1 PRODUCTS OF MANUFACTURE FOR THE TREATMENT, PREVENTION AND AMELIORATION OF MICROBIAL INFECTIONS CENTRE FOR DIGESTIVE DISEASES (AU) 2026-05-21 US claimed
EP-4094767-B1 NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO UNIV EMORY (US) 2026-05-20 EP claimed
US-20260102422-A1 4'-HALOGEN CONTAINING NUCLEOTIDE AND NUCLEOSIDE THERAPEUTIC COMPOSITIONS AND USES RELATED THERETO UNIV EMORY (US) 2026-04-16 US claimed
US-12595280-B2 Phosphoramidates for the treatment of hepatitis B virus EMORY UNIVERSITY (US) 2026-04-07 US claimed
US-20260092059-A1 Broad Spectrum Antiviral Compositions and Methods EVRYS BIO, LLC (US) 2026-04-02 US claimed
US-20260091068-A1 METHODS FOR TREATING AND PREVENTING DISEASES Tets, Viktor Veniaminovich (US) 2026-04-02 US claimed
EP-3534910-B1 RIFAMPICIN DERIVATIVES WITH ANTIBACTERIAL ACTIVITY POP TEST ONCOLOGY LLC (US) 2026-03-25 EP claimed
US-20260060964-A1 METHODS AND COMPOSITIONS FOR TREATING SEPSIS ANTIVIRUS THERAPEUTICS (US) 2026-03-05 US claimed
US-20260041660-A1 Compositions And Methods for Treating Acute Respiratory Distress Syndrome (ARDS) And Inflammatory Disorders Caused by Corona Viruses and Other Respiratory Pathogens or Agents That Mediate Pulmonary Injury, Inflammation or Acute Respiratory Distress, And Related Compositions and Methods for Treating and Preventing Human SARS Coronavirus Infection, COVID-19 Disease and Related Symptoms CHANG RICHARD L (US) 2026-02-12 US claimed
EP-4680248-A1 PRODUCTS OF MANUFACTURE AND THERAPEUTIC COMPOSITIONS FOR TREATING, AMELIORATING OR PREVENTING VIRAL INFECTIONS AND METHODS FOR MAKING AND USING THEM Topelia Aust Limited (ACN 652 771 670) (AU) 2026-01-21 EP claimed
CN-1634584-A Anti-cancer medicine composition containing antimetabolite SHANDONG LANJIN BIOENGINEERING (CN) 2005-07-06 CN claimed
CN-1634586-A Anti-cancer medicine composition SHANDONG LANJIN BIOENGINEERING (CN) 2005-07-06 CN claimed
WO-2005058226-A1 DERMAL DRUG DELIVERY SYSTEM MEDPHARM LIMITED (GB) 2005-06-30 WO claimed
US-20050118272-A1 Micronized pharmaceutical or nutraceutical powder with immediate release GALENIX INNOVATIONS (FR) 2005-06-02 US claimed
US-20050049220-A1 Dosing regimen for Flaviviridae therapy PHARMASSET, INC. 2005-03-03 US claimed
WO-2005018330-A1 DOSING REGIMEN FOR FLAVIVIRIDAE THERAPY PHARMASSET, INC. (US) 2005-03-03 WO claimed
US-20040132684-A1 Polymeric nucleoside prodrugs SAMPATH UMASHANKER (US) 2004-07-08 US claimed
US-20030124191-A1 Use of an immediate-release powder in pharmaceutical and nutraceutical compositions GALENIX INNOVATIONS (FR) 2003-07-03 US claimed
US-20020013287-A1 Polymeric compounds useful as prodrugs RELIABLE BIOPHARMACEUTICALS, INC. ST LOUIS MISSOURI 2002-01-31 US claimed
WO-2001085751-A1 POLYMERIC COMPOUNDS USEFUL AS PRODRUGS RELIABLE BIOPHARMACEUTICAL, INC. (US) 2001-11-15 WO claimed