Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL262074 | 1.00 | CRHBP (0.51) | CRHBPCRHR2ALDH1A1RECQLTP53 | |
| SCHEMBL261231 | 0.87 | KIF11 (0.54) | CRHBPCRHR2ALDH1A1RECQLHDAC3 | |
| SCHEMBL4110633 | 0.84 | CRHBP (0.51) | CRHBPCRHR2ALDH1A1RECQLTSHR | |
| SCHEMBL31357785 | 0.82 | CRHBP (0.55) | CRHBPCRHR2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL8786263 | 0.80 | CRHBP (0.49) | CRHBPCRHR2ALDH1A1RECQLHDAC3 | |
| SCHEMBL1574429 | 0.79 | AKR1C3 (0.58) | CRHBPCRHR2ALDH1A1HSD17B10LMNA | |
| Hydrochloric Acid SCHEMBL1410650 | 0.79 | CRHBP (0.48) | CRHBPCRHR2ALDH1A1RECQLHDAC3 | |
| SCHEMBL2815572 | 0.79 | NR1H4 (0.54) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL2170471 | 0.79 | NR1H4 (0.54) | ALDH1A1TP53TYRTSHRTAS2R38 | |
| SCHEMBL31149005 | 0.78 | CRHBP (0.50) | CRHBPCRHR2ALDH1A1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2346841-B1 | 2-ARYL-PROPIONIC ACIDS AND DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPÉ S P A (IT) | 2015-01-14 | — | — | EP | claimed |