Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.42 |
| ▸ | MME | P08473 | 5/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | QRFPR | Q96P65 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.37 |
| ▸ | NMT2 | O60551 | 2/20 | 0.36 |
| ▸ | NMT1 | P30419 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29542622 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 | |
| SCHEMBL31187165 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 | |
| SCHEMBL31219378 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 | |
| SCHEMBL31187142 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 | |
| SCHEMBL6749006 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 | |
| SCHEMBL6749004 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 | |
| SCHEMBL32669039 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 | |
| SCHEMBL16732006 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 | |
| SCHEMBL17874144 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 | |
| SCHEMBL29530559 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035452-B1 | Soluble heterodimeric receptors and uses thereof | NOVO NORDISK AS (DK) | 2012-04-25 | — | — | EP | disclosed |
| US-7932055-B2 | Soluble heterodimeric CD94/NKG2 receptors fusion proteins | NOVO NORDISK A/S (DK) | 2011-04-26 | — | — | US | disclosed |
| US-20090281035-A1 | Soluble Heterodimeric Receptors and Uses Thereof | NOVO NORDISK A/S (DK) | 2009-11-12 | — | — | US | disclosed |
| EP-2035452-A1 | SOLUBLE HETERODIMERIC RECEPTORS AND USES THEREOF | Novo Nordisk A/S (DK) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007147898-A1 | SOLUBLE HETERODIMERIC RECEPTORS AND USES THEREOF | NOVO NORDISK A/S (DK) | 2007-12-27 | — | — | WO | disclosed |
| EP-1144613-A4 | METHODS FOR MAKING PROTEINS CONTAINING FREE CYSTEINE RESIDUES | BOLDER BIOTECHNOLOGY INC (US) | 2002-10-29 | — | — | EP | disclosed |
| EP-1144613-A1 | METHODS FOR MAKING PROTEINS CONTAINING FREE CYSTEINE RESIDUES | Bolder Biotechnology, Inc. (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000042175-A1 | METHODS FOR MAKING PROTEINS CONTAINING FREE CYSTEINE RESIDUES | BOLDER BIOTECHNOLOGY INC. (US) | 2000-07-20 | — | — | WO | disclosed |