Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 3/20 | 0.42 |
| ▸ | MME | P08473 | 5/20 | 0.39 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | QRFPR | Q96P65 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.37 |
| ▸ | NMT2 | O60551 | 2/20 | 0.36 |
| ▸ | NMT1 | P30419 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29542622 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 | |
| SCHEMBL31187165 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 | |
| SCHEMBL31219378 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 | |
| SCHEMBL31187142 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 | |
| SCHEMBL6749004 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 | |
| SCHEMBL32669039 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 | |
| SCHEMBL16732006 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 | |
| SCHEMBL17874144 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 | |
| SCHEMBL1635449 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 | |
| SCHEMBL29530559 | 1.00 | TGFBR1 (0.42) | TGFBR1MMETERTQRFPRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12497439-B2 | Multi-functional fusion proteins and uses thereof | THOMAS JEFFERSON UNIVERSITY (US) | 2025-12-16 | — | — | US | disclosed |
| CN-113518823-B | Multifunctional fusion proteins and uses thereof | 托马斯杰斐逊大学 | 2025-05-02 | — | — | CN | disclosed |
| US-20220056102-A1 | MULTI-FUNCTIONAL FUSION PROTEINS AND USES THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2022-02-24 | — | — | US | disclosed |
| US-20040038378-A1 | Novel reagents for detection and purification of antibody fragments | HELLINGA HOMME W (US) | 2004-02-26 | — | — | US | disclosed |
| US-6663862-B1 | Separation of Fc fragments and Fab fragments of a human IgG. | DUKE UNIVERSITY | 2003-12-16 | — | — | US | disclosed |
| WO-2000074728-A1 | NOVEL REAGENTS FOR DETECTION AND PURIFICATION OF ANTIBODY FRAGMENTS | DUKE UNIVERSITY (US) | 2000-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220056102-A1 | MULTI-FUNCTIONAL FUSION PROTEINS AND USES THEREOF | RPS27A, IKZF2, GMFG | TGFBR1 3379/4885MME 319/4885TERT 2852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.