SCHEMBL16732006

SCHEMBL16732006

NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 3/20 0.42
MME P08473 5/20 0.39
TERT O14746 1/20 0.38
QRFPR Q96P65 3/20 0.38
PTGS1 P23219 1/20 0.37
GSTK1 Q9Y2Q3 1/20 0.37
NMT2 O60551 2/20 0.36
NMT1 P30419 2/20 0.36
CA2 P00918 2/20 0.33
OPRM1 P35372 1/20 0.33
OPRD1 P41143 1/20 0.33
CA1 P00915 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29542622 1.00 TGFBR1 (0.42) TGFBR1MMETERTQRFPRPTGS1
SCHEMBL31187165 1.00 TGFBR1 (0.42) TGFBR1MMETERTQRFPRPTGS1
SCHEMBL31219378 1.00 TGFBR1 (0.42) TGFBR1MMETERTQRFPRPTGS1
SCHEMBL31187142 1.00 TGFBR1 (0.42) TGFBR1MMETERTQRFPRPTGS1
SCHEMBL6749006 1.00 TGFBR1 (0.42) TGFBR1MMETERTQRFPRPTGS1
SCHEMBL6749004 1.00 TGFBR1 (0.42) TGFBR1MMETERTQRFPRPTGS1
SCHEMBL32669039 1.00 TGFBR1 (0.42) TGFBR1MMETERTQRFPRPTGS1
SCHEMBL17874144 1.00 TGFBR1 (0.42) TGFBR1MMETERTQRFPRPTGS1
SCHEMBL1635449 1.00 TGFBR1 (0.42) TGFBR1MMETERTQRFPRPTGS1
SCHEMBL29530559 1.00 TGFBR1 (0.42) TGFBR1MMETERTQRFPRPTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3630960-B1 METHOD FOR PREPARING PHOSPHORYLATED KETO POLYOLS, DERIVATIVES THEREOF AND USES THEREOF COMMISSARIAT ENERGIE ATOMIQUE (FR) 2023-12-13 EP disclosed
US-11466298-B2 Method for preparing phosphorylated keto polyols, derivatives thereof and uses thereof COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2022-10-11 US disclosed
US-20210317165-A1 ZP3 FRAGMENTS IN IMMUNOTHERAPY OF OVARIAN CANCER LABORATOIRE HRA-PHARMA (FR) 2021-10-14 US disclosed
US-11118200-B2 Method for preparing amines from aldehydes and ketones by biocatalysis COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2021-09-14 US disclosed
EP-3847187-A1 ZP3 FRAGMENTS IN IMMUNOTHERAPY OF OVARIAN CANCER Laboratoire HRA-Pharma (FR) 2021-07-14 EP disclosed
US-20200224225-A1 METHOD FOR PREPARING AMINES FROM ALDEHYDES AND KETONES BY BIOCATALYSIS UNIVERSITE D'EVRY VAL D'ESSONNE (UEVE) (FR) 2020-07-16 US disclosed
US-20200208181-A1 METHOD FOR PREPARING PHOSPHORYLATED KETO POLYOLS, DERIVATIVES THEREOF AND USES THEREOF UNIVERSITE D'EVRY VAL D'ESSONNE (FR) 2020-07-02 US disclosed
EP-3649246-A1 METHOD FOR PREPARING AMINES FROM ALDEHYDES AND KETONES BY BIOCATALYSIS Commissariat à l'énergie atomique et aux énergies alternatives (FR) 2020-05-13 EP disclosed
EP-3630960-A1 METHOD FOR PREPARING PHOSPHORYLATED KETO POLYOLS, DERIVATIVES THEREOF AND USES THEREOF Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2020-04-08 EP disclosed
WO-2019073011-A1 ENZYMATIC SYNTHESIS OF LIPOLANTHIPEPTIDES DEINOVE (FR) 2019-04-18 WO disclosed
WO-2019008110-A1 METHOD FOR PREPARING AMINES FROM ALDEHYDES AND KETONES BY BIOCATALYSIS COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2019-01-10 WO disclosed
WO-2018215476-A1 METHOD FOR PREPARING PHOSPHORYLATED KETO POLYOLS, DERIVATIVES THEREOF AND USES THEREOF COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2018-11-29 WO disclosed
WO-2015189162-A1 SINGLE-DOMAIN ANTIBODIES DIRECTED AGAINST A CYS-LOOP RECEPTOR AND METHODS FOR OBTAINING THEM THERANYX (FR) 2015-12-17 WO disclosed
WO-2015078889-A1 NEW ENZYMES AND METHOD FOR PREPARING HYDROXYLATED L-LYSINE OR L-ORNITHINE AND ANALOGS THEREOF COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-06-04 WO disclosed
EP-2876156-A1 New enzymes and method for preparing hydroxylated L-lysine or L-ornithine and analogs thereof COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) 2015-05-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11466298-B2 Method for preparing phosphorylated keto polyols, derivatives thereof and uses thereof PHYKPL, PNKP, PCK1 TGFBR1 4882/4885MME 3339/4885TERT 2724/4885
US-20200208181-A1 METHOD FOR PREPARING PHOSPHORYLATED KETO POLYOLS, DERIVATIVES THEREOF AND USES THEREOF PHYKPL, PNKP, PCK1 TGFBR1 4882/4885MME 3339/4885TERT 2724/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.