SCHEMBL1635451

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1636341	0.95	CYP11B1 (0.42)	CYP11B1AHRALDH1A1HPGDMAPT
	SCHEMBL22141168	0.93	AHR (0.49)	CYP11B1AHRALDH1A1HPGDMAPT
	SCHEMBL12037208	0.90	GPR84 (0.43)	CYP11B1AHRALDH1A1HPGDMAPT
	SCHEMBL12037041	0.90	GPR84 (0.43)	CYP11B1AHRALDH1A1HPGDMAPT
	SCHEMBL1635675	0.90	CYP11B1 (0.44)	CYP11B1AHRALDH1A1HPGDMAPT
	SCHEMBL25052391	0.89	MAPT (0.42)	CYP11B1AHRALDH1A1HPGDMAPT
	SCHEMBL12037042	0.89	GPR84 (0.43)	CYP11B1AHRALDH1A1HPGDMAPT
	SCHEMBL12037212	0.89	GPR84 (0.43)	CYP11B1AHRALDH1A1HPGDMAPT
	SCHEMBL16417791	0.89	GPR84 (0.46)	CYP11B1AHRALDH1A1HPGDMAPT
	SCHEMBL25050984	0.89	CYP11B1 (0.41)	CYP11B1AHRALDH1A1HPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.