SCHEMBL16355185

SCHEMBL16355185

CCOc1ccccc1C1(n2c(-c3ccccc3OC)nc(-c3ccccc3)c2-c2ccccc2)N=C(c2ccccc2)C(c2ccccc2)=N1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.43
GAA P10253 4/20 0.43
LMNA P02545 2/20 0.43
ALDH1A1 P00352 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.38
MGAM O43451 3/20 0.38
SI P14410 3/20 0.38
MGAM2 Q2M2H8 3/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
AKT1 P31749 4/20 0.37
AKT2 P31751 4/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
HPGD P15428 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HSD17B10 Q99714 1/20 0.35
DPP4 P27487 2/20 0.35
JAK2 O60674 1/20 0.35
JAK3 P52333 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4191996 0.95 GAA (0.38) KDM4EGAALMNAALDH1A1SMN1; SMN2
SCHEMBL29514957 0.95 GAA (0.38) KDM4EGAALMNAALDH1A1SMN1; SMN2
SCHEMBL29514758 0.92 KDM4E (0.48) KDM4EGAALMNAALDH1A1SMN1; SMN2
SCHEMBL16749580 0.92 KDM4E (0.48) KDM4EGAALMNAALDH1A1SMN1; SMN2
SCHEMBL27015236 0.86 KDM4E (0.43) KDM4EGAALMNAALDH1A1SMN1; SMN2
SCHEMBL23816808 0.84 MEN1 (0.37) KDM4EGAALMNAALDH1A1SMN1; SMN2
SCHEMBL16746554 0.83 KDM4E (0.40) KDM4EGAALMNAALDH1A1SMN1; SMN2
SCHEMBL18843390 0.80 L3MBTL1 (0.42) KDM4EGAALMNAALDH1A1SMN1; SMN2
SCHEMBL23816971 0.80 MCHR1 (0.33) KDM4EGAALMNAALDH1A1
SCHEMBL17133349 0.79 BCHE (0.36) KDM4EGAALMNAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140374677-A1 COLORED COMPOSITION, COLORED PHOTOSENSITIVE COMPOSITION, COLOR FILTER AND LIQUID CRYSTAL DISPLAY DEVICE EQUIPPED WITH SAME, ORGANIC EL DISPLAY DEVICE, AND SOLID-STATE IMAGE SENSOR FUJIFILM CORPORATION (JP) 2014-12-25 US disclosed
US-20140374677-A1 COLORED COMPOSITION, COLORED PHOTOSENSITIVE COMPOSITION, COLOR FILTER AND LIQUID CRYSTAL DISPLAY DEVICE EQUIPPED WITH SAME, ORGANIC EL DISPLAY DEVICE, AND SOLID-STATE IMAGE SENSOR FUJIFILM CORPORATION (JP) 2014-12-25 US disclosed