SCHEMBL16749580

SCHEMBL16749580

COc1ccccc1-c1nc(-c2ccccc2)c(-c2ccccc2)n1C1(c2ccccc2OC)N=C(c2ccccc2)C(c2ccccc2)=N1

nearest known ligand 0.49

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.48
ALDH1A1 P00352 3/20 0.48
LMNA P02545 2/20 0.48
GAA P10253 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.43
L3MBTL1 Q9Y468 3/20 0.41
MGAM O43451 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
MAPK1 P28482 1/20 0.38
RECQL P46063 1/20 0.38
AKT1 P31749 1/20 0.37
AKT2 P31751 1/20 0.37
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
DPP4 P27487 2/20 0.36
JAK2 O60674 1/20 0.36
JAK3 P52333 1/20 0.36
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29514758 1.00 KDM4E (0.48) KDM4EALDH1A1LMNAGAASMN1; SMN2
SCHEMBL27015236 0.94 KDM4E (0.43) KDM4EALDH1A1LMNAGAASMN1; SMN2
SCHEMBL16355185 0.92 KDM4E (0.43) KDM4EALDH1A1LMNAGAASMN1; SMN2
SCHEMBL16746554 0.89 KDM4E (0.40) KDM4EALDH1A1LMNAGAASMN1; SMN2
SCHEMBL29514957 0.86 GAA (0.38) KDM4EALDH1A1LMNAGAASMN1; SMN2
SCHEMBL4191996 0.86 GAA (0.38) KDM4EALDH1A1LMNAGAASMN1; SMN2
SCHEMBL18843390 0.85 L3MBTL1 (0.42) KDM4EALDH1A1LMNAGAASMN1; SMN2
SCHEMBL17133349 0.84 BCHE (0.36) KDM4EALDH1A1LMNAGAASMN1; SMN2
SCHEMBL17133351 0.84 KDM4E (0.48) KDM4EALDH1A1LMNAGAASMN1; SMN2
SCHEMBL18840155 0.83 KDM4E (0.41) KDM4EALDH1A1LMNAGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3976878-B1 METHODS OF MAKING A DEFLECTION MEMBER PROCTER & GAMBLE (US) 2023-07-05 EP claimed
US-11590694-B2 Methods of making a deflection member THE PROCTER & GAMBLE COMPANY (US) 2023-02-28 US claimed
US-20200378067-A1 METHODS OF MAKING A DEFLECTION MEMBER THE PROCTER & GAMBLE COMPANY 2020-12-03 US claimed
US-12583178-B2 Systems and methods for stereolithography three-dimensional printing Southwest Greene International, Inc. (US) 2026-03-24 US disclosed
US-20250312966-A1 METHODS OF MAKING A DEFLECTION MEMBER PROCTER & GAMBLE (US) 2025-10-09 US disclosed
US-12365132-B2 Methods of making a deflection member THE PROCTER & GAMBLE COMPANY (US) 2025-07-22 US disclosed
WO-2025026781-A1 METHOD FOR JOINING, POTTING, OR COATING SUBSTRATES, AND CURABLE COMPOUND FOR THIS PURPOSE DELO INDUSTRIE KLEBSTOFFE GMBH & CO. KGAA (DE) 2025-02-06 WO disclosed
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
US-20240153846-A1 SYSTEMS FOR THERMAL MANAGEMENT AND METHODS THEREOF HOLO, INC. 2024-05-09 US disclosed
US-20240140030-A1 SYSTEMS AND METHODS FOR STEREOLITHOGRAPHY THREE-DIMENSIONAL PRINTING Southwest Greene International, Inc. 2024-05-02 US disclosed
CN-117500656-A System and method for stereolithography three-dimensional printing 霍洛公司 2024-02-02 CN disclosed
EP-2899241-B1 PHOTOPOLYMERIZATION METHOD, INK SET, IMAGE FORMATION METHOD, INK COMPOSITION, AND PHOTOPOLYMERIZATION INITIATOR AND WATER-SOLUBLE BIIMIDAZOLE USED THEREIN FUJIFILM CORP (JP) 2019-08-28 EP disclosed
US-10324386-B2 Electrophotographic photoreceptor, image forming apparatus, image forming method, production method of electrophotographic photoreceptor Konica Minolta, Inc. (JP) 2019-06-18 US disclosed
US-20190176398-A1 METHODS AND SYSTEMS FOR STEROLITHOGRAPHY THREE-DIMENSIONAL PRINTING HOLO, INC. 2019-06-13 US disclosed
US-10245785-B2 Methods for stereolithography three-dimensional printing HOLO, INC. (US) 2019-04-02 US disclosed
US-20180361666-A1 METHODS AND SYSTEMS FOR STEREOLITHOGRAPHY THREE-DIMENSIONAL PRINTING Southwest Greene International, Inc. 2018-12-20 US disclosed
US-20180224761-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, PRODUCTION METHOD OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR Konica Minolta, Inc. (JP) 2018-08-09 US disclosed
US-9371460-B2 Photopolymerization method, ink set, ink composition, and water-soluble biimidazole FUJIFILM CORPORATION (JP) 2016-06-21 US disclosed
EP-2899241-A1 PHOTOPOLYMERIZATION METHOD, INK SET, IMAGE FORMATION METHOD, INK COMPOSITION, AND PHOTOPOLYMERIZATION INITIATOR AND WATER-SOLUBLE BIIMIDAZOLE USED THEREIN FUJI-FILM Corporation (JP) 2015-07-29 EP disclosed
US-20150148442-A1 PHOTOPOLYMERIZATION METHOD, INK SET, INK COMPOSITION, AND WATER-SOLUBLE BIIMIDAZOLE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150148442-A1 PHOTOPOLYMERIZATION METHOD, INK SET, INK COMPOSITION, AND WATER-SOLUBLE BIIMIDAZOLE JAK1, SETDB1, CCNI KDM4E 249/4885ALDH1A1 561/4885LMNA 3344/4885
US-12583178-B2 Systems and methods for stereolithography three-dimensional printing HTR3D, GLI1, SFRP1 KDM4E 2321/4885ALDH1A1 308/4885LMNA 2756/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.