SCHEMBL16746554

SCHEMBL16746554

COc1ccccc1C1(n2c(-c3ccccc3CO)nc(-c3ccccc3)c2-c2ccccc2)N=C(c2ccccc2)C(c2ccccc2)=N1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.40
GAA P10253 3/20 0.40
LMNA P02545 3/20 0.40
ALDH1A1 P00352 2/20 0.40
AKT1 P31749 2/20 0.36
AKT2 P31751 2/20 0.36
MGAM O43451 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
FABP4 P15090 2/20 0.34
FABP5 Q01469 2/20 0.34
HIF1A Q16665 1/20 0.34
EPAS1 Q99814 1/20 0.34
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16749580 0.89 KDM4E (0.48) KDM4EGAALMNAALDH1A1AKT1
SCHEMBL29514758 0.89 KDM4E (0.48) KDM4EGAALMNAALDH1A1AKT1
SCHEMBL27015236 0.87 KDM4E (0.43) KDM4EGAALMNAALDH1A1AKT1
SCHEMBL16355185 0.83 KDM4E (0.43) KDM4EGAALMNAALDH1A1AKT1
SCHEMBL1872357 0.81 ATR (0.35) GAAAKT1AKT2MGAMSI
SCHEMBL4191996 0.80 GAA (0.38) KDM4EGAALMNAALDH1A1AKT1
SCHEMBL29514957 0.80 GAA (0.38) KDM4EGAALMNAALDH1A1AKT1
SCHEMBL25778186 0.80 GAA (0.34) KDM4EGAALMNAALDH1A1AKT1
SCHEMBL25808944 0.80 PDCD1 (0.39) KDM4EGAALMNAALDH1A1AKT1
SCHEMBL18843390 0.79 L3MBTL1 (0.42) KDM4EGAALMNAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12032318-B2 Electrophotographic image forming system with cleaning blade Konica Minolta, Inc. (JP) 2024-07-09 US disclosed
US-20230185227-A1 ELECTROPHOTOGRAPHIC IMAGE FORMING SYSTEM Konica Minolta, Inc. (JP) 2023-06-15 US disclosed
US-20180224761-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, PRODUCTION METHOD OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR Konica Minolta, Inc. (JP) 2018-08-09 US disclosed
US-9371460-B2 Photopolymerization method, ink set, ink composition, and water-soluble biimidazole FUJIFILM CORPORATION (JP) 2016-06-21 US disclosed
US-20150148442-A1 PHOTOPOLYMERIZATION METHOD, INK SET, INK COMPOSITION, AND WATER-SOLUBLE BIIMIDAZOLE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150148442-A1 PHOTOPOLYMERIZATION METHOD, INK SET, INK COMPOSITION, AND WATER-SOLUBLE BIIMIDAZOLE JAK1, SETDB1, CCNI KDM4E 249/4885GAA 4119/4885LMNA 3344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.