Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22925137 | 0.84 | LMNA (0.62) | POLBMAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL24637463 | 0.78 | POLB (0.59) | POLBMAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL16609588 | 0.78 | KDM4E (0.68) | MAPTKDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL12780080 | 0.77 | CYP1A2 (0.61) | POLBMAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL165300 | 0.77 | CYP1A2 (0.61) | POLBMAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL165299 | 0.77 | CYP1A2 (0.61) | POLBMAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL2904986 | 0.76 | MAPT (0.53) | POLBMAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL7789028 | 0.75 | NPC1 (0.61) | POLBMAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL7793047 | 0.75 | GRIN2D (0.53) | POLBMAPTKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL7789023 | 0.75 | NPC1 (0.61) | POLBMAPTKDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9408392-B2 | Compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-09 | — | — | US | disclosed |
| US-20140378461-A1 | NOVEL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2014-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378461-A1 | NOVEL COMPOUNDS | CYP1B1, DDT, CYP51A1 | POLB 4051/4885MAPT 3602/4885KDM4E 1959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.