Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | PPARA | Q07869 | 2/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2949700 | 0.82 | SMN1; SMN2 (0.40) | MAPTALDH1A1PPARGPPARADRD1 | |
| SCHEMBL10593391 | 0.78 | DRD1 (0.46) | MAPTALDH1A1PPARGPPARADRD1 | |
| SCHEMBL10593386 | 0.78 | DRD1 (0.46) | MAPTALDH1A1PPARGPPARADRD1 | |
| SCHEMBL16355428 | 0.76 | POLB (0.52) | MAPTALDH1A1DRD1POLBKDM4E | |
| SCHEMBL7789028 | 0.76 | NPC1 (0.61) | MAPTALDH1A1DRD1POLBKDM4E | |
| SCHEMBL10663191 | 0.76 | ALDH1A1 (0.49) | MAPTALDH1A1PPARGPPARAKDM4E | |
| SCHEMBL10663187 | 0.76 | ALDH1A1 (0.49) | MAPTALDH1A1PPARGPPARAKDM4E | |
| SCHEMBL7793047 | 0.76 | GRIN2D (0.53) | MAPTALDH1A1DRD1POLBKDM4E | |
| SCHEMBL5438788 | 0.76 | RAB9A (0.53) | MAPTALDH1A1PPARGPPARAKMT2A | |
| SCHEMBL5438794 | 0.76 | RAB9A (0.53) | MAPTALDH1A1PPARGPPARAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106336383-B | A kind of trinitrogenazole alcohol analog derivative and its preparation method and application | 中国人民解放军第二军医大学 | 2019-05-14 | — | — | CN | disclosed |
| CN-106336383-A | Triazole alcohol derivative and preparation method and application thereof | 中国人民解放军第二军医大学 | 2017-01-18 | — | — | CN | disclosed |
| EP-1879884-B1 | AZOLE-BASED PHOSPHODIESTERASE INHIBITORS | RANBAXY LAB LTD (IN) | 2010-08-25 | — | — | EP | disclosed |
| EP-1879884-A1 | AZOLE-BASED PHOSPHODIESTERASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117653-A1 | AZOLE-BASED PHOSPHODIESTERASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |