Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 11/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1635563 | 0.81 | APP (0.68) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL12203258 | 0.81 | APP (0.68) | APPCYP1A2 | |
| SCHEMBL18216975 | 0.81 | HSD17B10 (0.50) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13926528 | 0.78 | RAB9A (0.44) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL21924480 | 0.78 | APP (0.43) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL17716522 | 0.76 | RAB9A (0.42) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL14338730 | 0.75 | MEN1 (0.51) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL13810526 | 0.75 | APP (0.43) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL308355 | 0.71 | CA2 (0.42) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL615340 | 0.71 | SMN1; SMN2 (0.58) | RAB9ANPC1SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11001562-B2 | Near-infrared fluorescent nerve contrast agents and methods of use thereof | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2021-05-11 | — | — | US | disclosed |
| US-20160347727-A1 | NEAR-INFRARED FLUORESCENT NERVE CONTRAST AGENTS AND METHODS OF USE THEREOF | BETH ISRAEL DEACONESS MEDICAL CT INC (US) | 2016-12-01 | — | — | US | disclosed |
| WO-2015066296-A9 | NEAR-INFRARED FLUORESCENT NERVE CONTRAST AGENTS AND METHODS OF USE THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2015-07-09 | — | — | WO | disclosed |
| WO-2015066296-A1 | NEAR-INFRARED FLUORESCENT NERVE CONTRAST AGENTS AND METHODS OF USE THEREOF | BETH ISRAEL DEACONESS MEDICAL CENTER (US) | 2015-05-07 | — | — | WO | disclosed |
| US-20130053252-A1 | NUCLEIC ACID AMPLIFICATION AND SEQUENCING BY SYNTHESIS WITH FLUOROGENIC NUCLEOTIDES | PRESIDENT & FELLOWS OF HARVARD COLLEGE (US) | 2013-02-28 | — | — | US | disclosed |
| US-8034928-B2 | Fluorescence assays with improved sensitivity | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-10-11 | — | — | US | disclosed |
| US-8034928-B2 | Fluorescence assays with improved sensitivity | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2011-10-11 | — | — | US | disclosed |
| WO-2010138960-A2 | METHODS AND SYSTEMS FOR SINGLE-MOLECULE RNA EXPRESSION PROFILING | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-12-02 | — | — | WO | disclosed |
| US-20100227327-A1 | METHODS AND COMPOSITIONS FOR CONTINUOUS SINGLE-MOLECULE NUCLEIC ACID SEQUENCING BY SYNTHESIS WITH FLUOROGENIC NUCLEOTIDES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-09-09 | — | — | US | disclosed |
| US-20100036110-A1 | METHODS AND COMPOSITIONS FOR CONTINUOUS SINGLE-MOLECULE NUCLEIC ACID SEQUENCING BY SYNTHESIS WITH FLUOROGENIC NUCLEOTIDES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2010-02-11 | — | — | US | disclosed |
| WO-2010017487-A1 | METHODS AND COMPOSITIONS FOR CONTINUOUS SINGLE-MOLECULE NUCLEIC ACID SEQUENCING BY SYNTHESIS WITH FLUOROGENIC NUCLEOTIDES | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2010-02-11 | — | — | WO | disclosed |
| US-20090299061-A1 | FLUORESCENCE ASSAYS WITH IMPROVED SENSITIVITY | PENN STATE RESEARCH FOUNDATION | 2009-12-03 | — | — | US | disclosed |
| US-20090299061-A1 | FLUORESCENCE ASSAYS WITH IMPROVED SENSITIVITY | PENN STATE RESEARCH FOUNDATION | 2009-12-03 | — | — | US | disclosed |
| US-7534902-B2 | Fluorescence assays with improved sensitivity | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-05-19 | — | — | US | disclosed |
| US-7534902-B2 | Fluorescence assays with improved sensitivity | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-05-19 | — | — | US | disclosed |
| US-20080213535-A1 | Oriented Zeolite Material and Method for Producing the Same | UNIVERSITAT BERN (CH) | 2008-09-04 | — | — | US | disclosed |
| US-20080213535-A1 | Oriented Zeolite Material and Method for Producing the Same | UNIVERSITAT BERN (CH) | 2008-09-04 | — | — | US | disclosed |
| WO-2007012216-A2 | ORIENTED ZEOLITE MATERIAL AND METHOD FOR PRODUCING THE SAME | Universität Bern (CH) | 2007-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100227327-A1 | METHODS AND COMPOSITIONS FOR CONTINUOUS SINGLE-MOLECULE NUCLEIC ACID SEQUENCING BY SYNTHESIS WITH FLUOROGENIC NUCLEOTIDES | RNGTT, NOP2, RNMT | RAB9A 2493/4885NPC1 438/4885SMN1; SMN2 1803/4885 |
| US-20160347727-A1 | NEAR-INFRARED FLUORESCENT NERVE CONTRAST AGENTS AND METHODS OF USE THEREOF | INA, NTRK1, NGF | RAB9A 1838/4885NPC1 713/4885SMN1; SMN2 49/4885 |
| US-20090299061-A1 | FLUORESCENCE ASSAYS WITH IMPROVED SENSITIVITY | UACA, HNRNPUL1, FUS | RAB9A 3862/4885NPC1 2630/4885SMN1; SMN2 4340/4885 |
| US-20130053252-A1 | NUCLEIC ACID AMPLIFICATION AND SEQUENCING BY SYNTHESIS WITH FLUOROGENIC NUCLEOTIDES | RNGTT, POLI, NT5E | RAB9A 2958/4885NPC1 1742/4885SMN1; SMN2 3671/4885 |
| US-11001562-B2 | Near-infrared fluorescent nerve contrast agents and methods of use thereof | INA, NTRK1, NGF | RAB9A 1838/4885NPC1 713/4885SMN1; SMN2 49/4885 |
| US-20100036110-A1 | METHODS AND COMPOSITIONS FOR CONTINUOUS SINGLE-MOLECULE NUCLEIC ACID SEQUENCING BY SYNTHESIS WITH FLUOROGENIC NUCLEOTIDES | RNGTT, DNMT3A, NOP2 | RAB9A 2733/4885NPC1 1028/4885SMN1; SMN2 1914/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.