Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 2/20 | 0.63 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.63 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NPR3 | P17342 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8336978 | 0.89 | ITGA4 (0.67) | ITGA4ITGB7ATMMAPTTDP1 | |
| SCHEMBL28293650 | 0.89 | ITGA4 (0.67) | ITGA4ITGB7ATMMAPTTDP1 | |
| SCHEMBL15876096 | 0.88 | ITGA4 (0.60) | ITGA4ITGB7MAPTTDP1POLB | |
| SCHEMBL2857976 | 0.86 | ITGA4 (0.64) | ITGA4ITGB7ATMMAPTTDP1 | |
| SCHEMBL5887224 | 0.86 | ITGA4 (0.64) | ITGA4ITGB7ATMMAPTTDP1 | |
| SCHEMBL5887302 | 0.86 | ITGA4 (0.64) | ITGA4ITGB7ATMMAPTTDP1 | |
| SCHEMBL5887295 | 0.86 | ITGA4 (0.64) | ITGA4ITGB7ATMMAPTTDP1 | |
| SCHEMBL5887221 | 0.86 | ITGA4 (0.64) | ITGA4ITGB7ATMMAPTTDP1 | |
| SCHEMBL2857974 | 0.86 | ITGA4 (0.64) | ITGA4ITGB7ATMMAPTTDP1 | |
| SCHEMBL19511478 | 0.82 | ITGA4 (0.42) | ITGA4ITGB7ATMSMN1; SMN2SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9199927-B2 | Guanidinobenzoic acid compound | ASTELLAS PHARMA INC. (JP) | 2015-12-01 | — | — | US | disclosed |
| US-20140378459-A1 | GUANIDINOBENZOIC ACID COMPOUND | ASTELLAS PHARMA INC. (JP) | 2014-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378459-A1 | GUANIDINOBENZOIC ACID COMPOUND | SERPINB1, REN, SPINT2 | ITGA4 4760/4885ITGB7 4771/4885ATM 3268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.