Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14839449 | 0.87 | MDM2 (0.54) | MDM2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL14839452 | 0.83 | MDM2 (0.56) | MDM2NPC1RAB9AALDH1A1MAPK9 | |
| SCHEMBL16356387 | 0.81 | MDM2 (0.51) | MDM2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL1155787 | 0.77 | MDM2 (0.55) | MDM2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL28004022 | 0.77 | MAPK9 (0.54) | MDM2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL5907310 | 0.74 | MAPK9 (0.56) | MDM2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL12759885 | 0.73 | MDM2 (0.52) | MDM2NPC1RAB9AALDH1A1LMNA | |
| SCHEMBL17086633 | 0.73 | MDM2 (0.52) | MDM2NPC1RAB9AALDH1A1MAPK9 | |
| SCHEMBL15083811 | 0.72 | MDM2 (0.40) | MDM2ALDH1A1MAPK9MAPK10MAPK8 | |
| SCHEMBL15574080 | 0.72 | ALDH1A1 (0.43) | MDM2NPC1RAB9AALDH1A1MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150243910-A1 | TRANSITION METAL COMPLEXES COMPRISING ASYMMETRIC TETRADENTATE LIGANDS | SOLVAY (BE) | 2015-08-27 | — | — | US | disclosed |
| US-20150221877-A1 | TRANSITION METAL COMPLEXES COMPRISING SYMMETRIC TETRADENTATE LIGANDS | SOLVAY (BE) | 2015-08-06 | — | — | US | disclosed |
| US-20140378685-A1 | PREPARATION OF HETEROLEPTIC METAL COMPLEXES | SOLVAY SA (BE) | 2014-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150221877-A1 | TRANSITION METAL COMPLEXES COMPRISING SYMMETRIC TETRADENTATE LIGANDS | AP2M1, AP3M1, AP1M1 | MDM2 73/4885NPC1 2101/4885RAB9A 1874/4885 |
| US-20150243910-A1 | TRANSITION METAL COMPLEXES COMPRISING ASYMMETRIC TETRADENTATE LIGANDS | AP2M1, AP3M1, AP1M1 | MDM2 31/4885NPC1 2539/4885RAB9A 1956/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.