SCHEMBL16356909

SCHEMBL16356909

NCCNC(=O)CCN(CCNC(=O)CCN(CCO)CCC(=O)NCCN(CCC(=O)NCCN)CCC(=O)NCCN)CCC(=O)NCCN

nearest known ligand 0.83

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.34
KDM4A O75164 1/20 0.33
HIF1A Q16665 1/20 0.33
TET2 Q6N021 1/20 0.33
DOHH Q9BU89 1/20 0.33
NAAA Q02083 1/20 0.33
GAA P10253 2/20 0.31
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA9 Q16790 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16356912 0.96 NAAA (0.35) DNM1KDM4AHIF1ATET2DOHH
SCHEMBL16985018 0.95 NAAA (0.34) DNM1KDM4AHIF1ATET2DOHH
SCHEMBL16356888 0.92 DNM1 (0.40) DNM1KDM4AHIF1ATET2DOHH
SCHEMBL16984922 0.91 GAA (0.36) DNM1KDM4AHIF1ATET2DOHH
SCHEMBL16356913 0.91 DNM1 (0.36) DNM1KDM4AHIF1ATET2DOHH
SCHEMBL8239576 0.91 DNM1 (0.37) DNM1KDM4AHIF1ATET2DOHH
Poly(Amidoamine)Dendrimer SCHEMBL13964588 0.91 DNM1 (0.37) DNM1KDM4AHIF1ATET2DOHH
SCHEMBL12219612 0.89 KDM4A (0.38) DNM1KDM4AHIF1ATET2DOHH
SCHEMBL16356885 0.88 NAAA (0.41) DNM1NAAAGAA
SCHEMBL16509435 0.87 KDM4A (0.40) DNM1KDM4AHIF1ATET2DOHH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160369064-A1 DENDRITIC POLYMER, DENDRITIC POLYMER MONOMER, AND HYPERBRANCHED COPOLYMER CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-12-22 US disclosed
US-20160369064-A1 DENDRITIC POLYMER, DENDRITIC POLYMER MONOMER, AND HYPERBRANCHED COPOLYMER CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-12-22 US disclosed
US-9475894-B2 Dendritic polymer, dendritic polymer monomer, and hyperbranched copolymer CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-10-25 US disclosed
US-9475894-B2 Dendritic polymer, dendritic polymer monomer, and hyperbranched copolymer CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-10-25 US disclosed
US-20140378638-A1 DENDRITIC POLYMER, DENDRITIC POLYMER MONOMER, AND HYPERBRANCHED COPOLYMER CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2014-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160369064-A1 DENDRITIC POLYMER, DENDRITIC POLYMER MONOMER, AND HYPERBRANCHED COPOLYMER ZYX, F12, NPY5R DNM1 341/4885KDM4A 3419/4885HIF1A 3274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.