SCHEMBL16985018

SCHEMBL16985018

NCCNC(=O)CCN(CCO)CCN(CCC(=O)NCCN)CCC(=O)NCCN

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.34
DNM1 Q05193 2/20 0.34
KDM4A O75164 1/20 0.34
HIF1A Q16665 1/20 0.34
TET2 Q6N021 1/20 0.34
DOHH Q9BU89 1/20 0.34
KDM4E B2RXH2 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
GAA P10253 2/20 0.32
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
TSHR P16473 1/20 0.30
CYP2C19 P33261 1/20 0.30
SLC6A5 Q9Y345 1/20 0.30
CNR1 P21554 1/20 0.30
ALDH1A1 P00352 1/20 0.30
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16356912 0.98 NAAA (0.35) NAAADNM1KDM4AHIF1ATET2
SCHEMBL16356909 0.95 DNM1 (0.34) NAAADNM1KDM4AHIF1ATET2
SCHEMBL16984922 0.93 GAA (0.36) NAAADNM1KDM4AHIF1ATET2
SCHEMBL24625968 0.92 KDM4A (0.37) DNM1KDM4AHIF1ATET2DOHH
SCHEMBL10194547 0.92 KDM4A (0.37) DNM1KDM4AHIF1ATET2DOHH
SCHEMBL16984940 0.92 KDM4A (0.37) DNM1KDM4AHIF1ATET2DOHH
SCHEMBL12219612 0.90 KDM4A (0.38) DNM1KDM4AHIF1ATET2DOHH
SCHEMBL16356885 0.90 NAAA (0.41) NAAADNM1GAASLC6A5CNR1
SCHEMBL8239576 0.89 DNM1 (0.37) DNM1KDM4AHIF1ATET2DOHH
SCHEMBL13374199 0.89 KDM4A (0.36) DNM1KDM4AHIF1ATET2DOHH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150217236-A1 SEPARATION MEMBRANE, COMPOSITE SEPARATION MEMBRANE, AND METHOD FOR PRODUCING SEPARATION MEMBRANE NITTO DENKO CORPORATION (JP) 2015-08-06 US disclosed