SCHEMBL1635693

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1637406	0.96	PDK2 (0.37)	MAOAPDK2HSP90AA1HSP90AB1PLA2G2A
	SCHEMBL16017881	0.96	PDK2 (0.38)	PDK2HSP90AA1HSP90AB1PLA2G2APLA2G4A
	SCHEMBL9890029	0.94	PRKDC (0.40)	MAOAPDK2PLA2G2APLA2G4APGR
	SCHEMBL1637658	0.91	PRKDC (0.40)	MAOAPDK2PLA2G2APLA2G4APGR
	SCHEMBL18086158	0.91	HSP90AA1 (0.43)	MAOAPDK2HSP90AA1HSP90AB1PLA2G2A
	SCHEMBL16017880	0.91	HSP90AA1 (0.43)	MAOAPDK2HSP90AA1HSP90AB1PLA2G2A
	SCHEMBL25052976	0.91	HSP90AA1 (0.36)	MAOAPDK2HSP90AA1HSP90AB1PLA2G2A
	SCHEMBL13060946	0.90	MAOA (0.33)	MAOAPDK2HSP90AA1HSP90AB1
	SCHEMBL24362851	0.90	MAOA (0.39)	MAOAPDK2HSP90AA1HSP90AB1PLA2G2A
	SCHEMBL25052716	0.89	PDK2 (0.36)	MAOAPDK2HSP90AA1HSP90AB1PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.