Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1635695 | 0.82 | ALDH1A1 (0.38) | HPGDALDH1A1MAPTL3MBTL1LMNA | |
| SCHEMBL1636978 | 0.82 | ACACB (0.41) | HPGDTDP1ALDH1A1MAPTNPC1 | |
| SCHEMBL1637052 | 0.80 | ATM (0.49) | HPGDTDP1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1637036 | 0.79 | ALDH1A1 (0.36) | TDP1ALDH1A1MAPTLMNARAB9A | |
| SCHEMBL1636089 | 0.79 | ALDH1A1 (0.48) | HPGDTDP1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1636086 | 0.75 | MAPT (0.43) | TDP1ALDH1A1MAPTL3MBTL1SMN1; SMN2 | |
| SCHEMBL1636350 | 0.75 | TTR (0.40) | HPGDTDP1ALDH1A1MAPTLMNA | |
| SCHEMBL1637166 | 0.74 | SMN1; SMN2 (0.42) | HPGDTDP1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL1636094 | 0.73 | HPGD (0.61) | HPGDTDP1ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL4918506 | 0.73 | HPGD (0.61) | HPGDTDP1ALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2042506-B1 | SUBSTITUTED PHENYLETHYNYL GOLD-NITROGENATED HETEROCYCLIC CARBENE COMPLEX | UBE INDUSTRIES (JP) | 2012-12-19 | — | — | EP | disclosed |
| US-7932398-B2 | Substituted phenylethynylgold-nitrogen-containing heterocyclic carbene complex | UBE INDUSTRIES, LTD. (JP) | 2011-04-26 | — | — | US | disclosed |
| US-20090234130-A1 | SUBSTITUTED PHENYLETHYNYLGOLD-NITROGEN-CONTAINING HETEROCYCLIC CARBENE COMPLEX | UBE INDUSTRIES, LTD. (JP) | 2009-09-17 | — | — | US | disclosed |
| EP-2042506-A1 | SUBSTITUTED PHENYLETHYNYL GOLD-NITROGENATED HETEROCYCLIC CARBENE COMPLEX | Ube Industries, Ltd. (JP) | 2009-04-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090234130-A1 | SUBSTITUTED PHENYLETHYNYLGOLD-NITROGEN-CONTAINING HETEROCYCLIC CARBENE COMPLEX | CCRL2, CCNL2, ATXN2L | HPGD 3064/4885TDP1 4727/4885ALDH1A1 3101/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.