Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 10/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 3/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8221255 | 0.88 | ADAM17 (0.55) | ADAM17MEN1KMT2ANAMPTTAS1R3 | |
| SCHEMBL8221408 | 0.88 | ADAM17 (0.51) | ADAM17MEN1KMT2ANAMPTTAS1R3 | |
| SCHEMBL8274846 | 0.86 | ADAM17 (0.61) | ADAM17MEN1KMT2ANAMPTTAS1R3 | |
| SCHEMBL8273353 | 0.86 | ADAM17 (0.61) | ADAM17MEN1KMT2ANAMPTTAS1R3 | |
| SCHEMBL8213991 | 0.82 | ADAM17 (0.55) | ADAM17MEN1KMT2ANAMPTTAS1R3 | |
| SCHEMBL8221019 | 0.81 | LDHA (0.51) | ADAM17MEN1KMT2ALDHAKDM4E | |
| SCHEMBL8222661 | 0.79 | ADAM17 (0.53) | ADAM17MEN1KMT2ACHRM4 | |
| SCHEMBL8213656 | 0.79 | ADAM17 (0.54) | ADAM17MEN1KMT2ANAMPTCHRM4 | |
| SCHEMBL8213653 | 0.79 | CHRM4 (0.49) | ADAM17CHRM4 | |
| SCHEMBL8276637 | 0.78 | ADAM17 (0.53) | ADAM17NAMPTTAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007064749-A1 | COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS AND MICROBIAL DISEASES | SCHERING CORPORATION (US) | 2007-06-07 | — | — | WO | disclosed |