SCHEMBL1635798

SCHEMBL1635798

CCCCCc1cc(=O)cc2oc3cc(N)ccc3nc1-2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.44
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
APP P05067 4/20 0.37
NPC1 O15118 3/20 0.37
RAB9A P51151 3/20 0.37
MAPT P10636 3/20 0.37
ALDH1A1 P00352 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CYP1A2 P05177 1/20 0.37
KDM4E B2RXH2 1/20 0.37
GLA P06280 1/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 1/20 0.37
POLB P06746 3/20 0.37
TLR8 Q9NR97 6/20 0.37
ELANE P08246 1/20 0.37
USP2 O75604 2/20 0.35
HTT P42858 1/20 0.35
HCAR2 Q8TDS4 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5479204 0.84 MAPT (0.42) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL1636725 0.80 SRC (0.47) SRCMEN1KMT2AAPPNPC1
SCHEMBL11792767 0.74 MAPT (0.51) SRCMEN1KMT2ANPC1RAB9A
SCHEMBL21814974 0.70 MEN1 (0.56) SRCMEN1KMT2ANPC1RAB9A
SCHEMBL1635260 0.70 RAB9A (0.44) SRCMEN1KMT2AAPPNPC1
SCHEMBL11878333 0.70 SRC (0.58) SRCMEN1KMT2ANPC1RAB9A
SCHEMBL27310713 0.69 RAB9A (0.46) MEN1KMT2AAPPNPC1RAB9A
SCHEMBL30898571 0.69 RAB9A (0.46) MEN1KMT2AAPPNPC1RAB9A
SCHEMBL738742 0.68 APP (0.59) APPMAPTCYP1A2TLR8
SCHEMBL3274196 0.67 ADORA2A (0.39) MEN1KMT2AAPPNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10546651-B2 Modifying a cosmetic product based on a microbe profile ELWHA LLC (US) 2020-01-28 US disclosed
EP-3031928-B1 QUICK METHOD FOR DETECTING ENZYMES AND MICRO-ORGANISMS BIO RAD INNOVATIONS (FR) 2019-11-20 EP disclosed
US-20190147984-A1 Modifying a Cosmetic Product Based on a Microbe Profile ELWHA LLC (US) 2019-05-16 US disclosed
US-10140424-B2 Modifying a cosmetic product based on a microbe profile ELWHA LLC (US) 2018-11-27 US disclosed
US-20170364665-A1 Modifying a Cosmetic Product Based on a Microbe Profile ELWHA LLC (US) 2017-12-21 US disclosed
US-9811641-B2 Modifying a cosmetic product based on a microbe profile ELWHA LLC (US) 2017-11-07 US disclosed
US-9805171-B2 Modifying a cosmetic product based on a microbe profile ELWHA LLC (US) 2017-10-31 US disclosed
EP-3044712-A1 MODIFYING A COSMETIC PRODUCT BASED ON A MICROBE PROFILE ELWHA, LLC (US) 2016-07-20 EP disclosed
EP-3031928-A1 QUICK METHOD FOR DETECTING ENZYMES AND MICRO-ORGANISMS Bio-Rad Innovations (FR) 2016-06-15 EP disclosed
EP-2542688-B1 QUICK METHOD FOR DETECTING ENZYMES AND MICRO-ORGANISMS BIO RAD INNOVATIONS (FR) 2016-05-11 EP disclosed
US-20130089883-A1 QUICK METHOD FOR DETECTING ENYZMES AND MICROORANISMS BIO-RAD INNOVATIONS (FR) 2013-04-11 US disclosed
EP-2542688-A1 QUICK METHOD FOR DETECTING ENZYMES AND MICRO-ORGANISMS Bio-Rad Innovations (FR) 2013-01-09 EP disclosed
EP-1786828-B1 NOVEL ENZYMATIC SUBSTRATES DERIVED FROM PHENOXAZINONE AND THEIR USE AS DEVELOPER IN DETECTION OF MICRO-ORGANISM WITH PEPTIDASE ACTIVITY BIOMERIEUX SA (FR) 2012-01-11 EP disclosed
WO-2011107703-A1 QUICK METHOD FOR DETECTING ENZYMES AND MICRO-ORGANISMS BIO-RAD PASTEUR (FR) 2011-09-09 WO disclosed
US-7932050-B2 Enzymatic substrates derived from phenoxazinone and their use as developers in detection of microorganisms with peptidase activity BIOMERIEUX (FR) 2011-04-26 US disclosed
US-20100028926-A1 Novel enzymatic substrates derived from phenoxazinone and their use as developer in detection of microorganisms with peptidase activity BIOMERIEUX (FR) 2010-02-04 US disclosed
US-7626018-B2 Enzymatic substrates derived from phenoxazinone and their use as developer in detection of microorganisms with peptidase activity bioMérieux (FR) 2009-12-01 US disclosed
US-20080293094-A1 Novel Enzymatic Substrates Derived from Phenoxazinone and Their Use as Developer in Detection of Microorganisms with Peptidase Activity BIOMERIEUX (FR) 2008-11-27 US disclosed
EP-1786828-A1 NOVEL ENZYMATIC SUBSTRATES DERIVED FROM PHENOXAZINONE AND THEIR USE AS DEVELOPER IN DETECTION OF MICRO-ORGANISM WITH PEPTIDASE ACTIVITY BIOMERIEUX (FR) 2007-05-23 EP disclosed
WO-2006030119-A1 NOVEL ENZYMATIC SUBSTRATES DERIVED FROM PHENOXAZINONE AND THEIR USE AS DEVELOPER IN DETECTION OF MICRO-ORGANISM WITH PEPTIDASE ACTIVITY bioMérieux (FR) 2006-03-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293094-A1 Novel Enzymatic Substrates Derived from Phenoxazinone and Their Use as Developer in Detection of Microorganisms with Peptidase Activity PEPD, CTRL, PREP SRC 3259/4885MEN1 1786/4885KMT2A 3459/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.