Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | EIF4A1 | P60842 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601681 | 0.99 | APP (0.58) | APPCYP1A2EIF4A1MAPTTLR8 | |
| SCHEMBL3104713 | 0.86 | APP (0.55) | APPCYP1A2TLR8 | |
| SCHEMBL563769 | 0.85 | APP (0.66) | APPCYP1A2MAPT | |
| SCHEMBL119047 | 0.84 | APP (0.56) | APPCYP1A2MAPT | |
| SCHEMBL5681747 | 0.83 | APP (0.55) | APPCYP1A2MAPT | |
| SCHEMBL5710520 | 0.83 | APP (0.55) | APPCYP1A2MAPT | |
| SCHEMBL10208641 | 0.83 | APP (0.64) | APPCYP1A2MAPT | |
| Glucuronate SCHEMBL9538374 | 0.83 | APP (0.43) | APPCYP1A2EIF4A1 | |
| SCHEMBL4922053 | 0.83 | APP (0.57) | APPCYP1A2 | |
| SCHEMBL5710642 | 0.82 | APP (0.54) | APPCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5336600-A | Incubating samples with fluorescent reagent which has observable decrease in emitted light in presence of microorganisms, kits for screening blood, urine, foods, water drugs or cosmetics | BIO MERIEUX (FR) | 1994-08-09 | — | — | US | claimed |
| US-8137925-B2 | Methods and compositions for protein labeling using lipoic acid ligases | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2012-03-20 | — | — | US | disclosed |