Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666115 | 0.69 | RAB9A (0.46) | ADORA2ANPC1MEN1RAB9AKMT2A | |
| SCHEMBL3275224 | 0.69 | KMT2A (0.62) | NPC1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL12984911 | 0.68 | APP (0.57) | MEN1KMT2AKDM4EHPGDAPP | |
| SCHEMBL1635798 | 0.67 | SRC (0.44) | NPC1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL1635563 | 0.67 | APP (0.68) | NPC1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL1635260 | 0.67 | RAB9A (0.44) | NPC1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL826022 | 0.64 | KMT2A (0.45) | ADORA2ANPC1MEN1RAB9AKMT2A | |
| SCHEMBL28236480 | 0.63 | RAB9A (0.67) | NPC1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL13338326 | 0.63 | LCK (0.52) | NPC1MEN1RAB9AKMT2AMAPT | |
| SCHEMBL6235497 | 0.62 | PIK3R1 (0.66) | ADORA2AMEN1RAB9AKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7695930-B2 | Method for the detection, identification and/or quantification of microoganisms with peptidase activity using phenoxazinone derivatives as enzyme substrates | BIOMERIEUX (FR) | 2010-04-13 | — | — | US | disclosed |
| US-20080286820-A1 | Novel phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity | BIOMERIEUX (FR) | 2008-11-20 | — | — | US | disclosed |
| US-7420054-B2 | Phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity | BIOMERIEUX (FR) | 2008-09-02 | — | — | US | disclosed |
| EP-1625117-B1 | NOVEL PHENOXAZINONE DERIVATIVES AS ENZYME SUBSTRATES AND USE THEREOF AS INDICTOR IN THE DETECTION OF MICROORGANISMS WITH PEPTIDASE ACTIVITY | BIOMERIEUX SA (FR) | 2008-01-09 | — | — | EP | disclosed |
| US-20060121551-A1 | Novel phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity | BIOMERIEUX (FR) | 2006-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060121551-A1 | Novel phenoxazinone derivatives as enzyme substrates and use thereof as indicator in the detection of microorganisms with peptidase activity | PEPD, CTRL, PM20D2 | ADORA2A 2986/4885NPC1 4472/4885MEN1 2241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.