Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29767252 | 0.71 | SCN2A (0.59) | ALDH1A1PKMKDM4EGAASCN2A | |
| SCHEMBL2303248 | 0.71 | SCN2A (0.59) | ALDH1A1PKMKDM4EGAASCN2A | |
| SCHEMBL26079051 | 0.70 | TDP1 (0.47) | ALDH1A1GAA | |
| SCHEMBL13977951 | 0.69 | AGXT (0.52) | KDM4EGAALMNA | |
| SCHEMBL13866492 | 0.66 | KCNA3 (0.44) | ALDH1A1LMNA | |
| SCHEMBL16525693 | 0.66 | — | — | |
| SCHEMBL17916656 | 0.65 | — | — | |
| SCHEMBL11826455 | 0.65 | ALDH1A1 (0.56) | ALDH1A1PKMKDM4EGAALMNA | |
| SCHEMBL14922940 | 0.65 | DRD2 (0.41) | GAA | |
| SCHEMBL13082241 | 0.64 | ALDH1A1 (0.60) | ALDH1A1PKMKDM4EGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151597-A1 | METHODS FOR USING PYRROLO-BENZO-1,4-DIAZINES AS SODIUM CHANNEL BLOCKERS | SCHERING CORPORATION (US) | 2010-12-29 | — | — | WO | disclosed |
| WO-2010151595-A1 | PYRROLO-BENZO-1,4-DIAZINES USEFUL AS SODIUM CHANNEL BLOCKERS | SCHERING CORPORATION (US) | 2010-12-29 | — | — | WO | disclosed |