Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | FOLH1 | Q04609 | 5/20 | 0.46 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.46 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 3/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.45 |
| ▸ | MMP8 | P22894 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | BMP1 | P13497 | 3/20 | 0.42 |
| ▸ | GABRP | O00591 | 2/20 | 0.41 |
| ▸ | GABRD | O14764 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22489300 | 1.00 | HPGDS (0.46) | HPGDSFOLH1NAALAD2RIMKLAMMP12 | |
| SCHEMBL31622132 | 1.00 | HPGDS (0.46) | HPGDSFOLH1NAALAD2RIMKLAMMP12 | |
| SCHEMBL27585071 | 0.88 | NOD1 (0.51) | NOD1PTPN1 | |
| SCHEMBL12324667 | 0.87 | MMP12 (0.47) | HPGDSFOLH1NAALAD2RIMKLAMMP12 | |
| SCHEMBL26173989 | 0.87 | FOLH1 (0.47) | FOLH1NAALAD2RIMKLANOD1BMP1 | |
| SCHEMBL26394477 | 0.85 | NOD1 (0.40) | HPGDSMMP12MMP2MMP8CA12 | |
| SCHEMBL3287762 | 0.85 | FOLH1 (0.64) | FOLH1NAALAD2RIMKLANOD1GNPAT | |
| SCHEMBL3287759 | 0.85 | FOLH1 (0.64) | FOLH1NAALAD2RIMKLANOD1GNPAT | |
| SCHEMBL20539219 | 0.85 | FOLH1 (0.64) | FOLH1NAALAD2RIMKLANOD1GNPAT | |
| SCHEMBL11568946 | 0.85 | NOD1 (0.42) | FOLH1CA12CA1CA9NOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053548-A2 | PTHR1 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |