Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.39 |
| ▸ | CIT | O14578 | 1/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 6/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 5/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.34 |
| ▸ | ECE1 | P42892 | 2/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | FCER2 | P06734 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | CPA1 | P15085 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 2/20 | 0.32 |
| ▸ | IL1RN | P18510 | 2/20 | 0.32 |
| ▸ | GRB2 | P62993 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31020879 | 0.98 | ACE (0.38) | ACECITERAP2ERAP1LNPEP | |
| SCHEMBL30874984 | 0.91 | ACE (0.42) | ACEMMECPA1ACE2 | |
| SCHEMBL15011307 | 0.91 | ACE (0.42) | ACEMMECPA1ACE2 | |
| SCHEMBL15011306 | 0.91 | ACE (0.42) | ACEMMECPA1ACE2 | |
| SCHEMBL29517172 | 0.89 | ERAP2 (0.35) | ACEERAP2ERAP1LNPEPECE1 | |
| SCHEMBL29384685 | 0.89 | ECE1 (0.37) | ACEERAP2ERAP1LNPEPECE1 | |
| Hydrochloric Acid SCHEMBL10448582 | 0.87 | ALDH1A1 (0.36) | CITERAP2ERAP1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL10448581 | 0.87 | ALDH1A1 (0.36) | CITERAP2ERAP1KDM4EMAPT | |
| SCHEMBL31020882 | 0.87 | ECE1 (0.36) | ERAP2ERAP1LNPEPECE1MMP1 | |
| SCHEMBL31318666 | 0.85 | ENPEP (0.41) | ACELNPEPMMECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053548-A2 | PTHR1 RECEPTOR COMPOUNDS | ANCHOR THERAPEUTICS, INC. (US) | 2010-05-14 | — | — | WO | disclosed |