SCHEMBL31020882

SCHEMBL31020882

CC(C)[C@H](N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](Cc1c[nH]cn1)C(N)=O

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ECE1 P42892 2/20 0.36
▸ CTSC P53634 1/20 0.35
▸ REN P00797 2/20 0.35
▸ ERAP2 Q6P179 8/20 0.34
▸ ERAP1 Q9NZ08 7/20 0.34
▸ LNPEP Q9UIQ6 7/20 0.34
▸ MMP1 P03956 1/20 0.34
▸ FCER2 P06734 1/20 0.34
▸ DPP4 P27487 1/20 0.33
▸ FAP Q12884 1/20 0.33
▸ DPP8 Q6V1X1 1/20 0.33
▸ DPP9 Q86TI2 1/20 0.33
▸ DPP7 Q9UHL4 1/20 0.33
▸ ANPEP P15144 2/20 0.32
▸ IL1RN P18510 2/20 0.32
▸ GHSR Q92847 1/20 0.32
▸ CTSL P07711 1/20 0.32
▸ PTPN1 P18031 1/20 0.32
▸ NPY4R P50391 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29384685 0.97 ECE1 (0.37) ECE1CTSCRENERAP2ERAP1
SCHEMBL29517172 0.90 ERAP2 (0.35) ECE1RENERAP2ERAP1LNPEP
SCHEMBL31020879 0.90 ACE (0.38) ECE1RENERAP2ERAP1LNPEP
SCHEMBL78173 0.88 ACE (0.36) ECE1CTSCDPP4FAPDPP8
SCHEMBL79320 0.88 ACE (0.36) ECE1CTSCDPP4FAPDPP8
SCHEMBL78174 0.88 ACE (0.36) ECE1CTSCDPP4FAPDPP8
SCHEMBL30129742 0.88 ECE1 (0.43) ECE1CTSC
SCHEMBL29881377 0.87 CTSD (0.35) ECE1CTSCLNPEPANPEP
SCHEMBL16359592 0.87 ACE (0.39) ECE1ERAP2ERAP1LNPEPMMP1
SCHEMBL3750892 0.86 MME (0.41) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240197815-A1 METHODS AND COMPOSITIONS FOR IMPROVING VISUAL FUNCTION IN OCULAR DISEASES AND DISORDERS ONL THERAPEUTICS, INC. 2024-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240197815-A1 METHODS AND COMPOSITIONS FOR IMPROVING VISUAL FUNCTION IN OCULAR DISEASES AND DISORDERS PDE6C, UACA, EYA3 ECE1 2169/4885CTSC 457/4885REN 850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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