Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | RXRB | P28702 | 1/20 | 0.35 |
| ▸ | RXRG | P48443 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29531338 | 1.00 | S1PR3 (0.35) | S1PR3RXRARXRBRXRGALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL31717922 | 0.90 | S1PR3 (0.32) | S1PR3RXRARXRBRXRGCYP26B1 | |
| SCHEMBL30486061 | 0.86 | LMNA (0.36) | CYP26B1CYP26A1LMNAKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL31558565 | 0.85 | KDM1A (0.38) | LMNA | |
| SCHEMBL14080041 | 0.84 | RXRA (0.33) | S1PR3RXRARXRBRXRGALDH1A1 | |
| SCHEMBL31657046 | 0.82 | S1PR3 (0.32) | S1PR3RXRARXRBRXRGCA1 | |
| SCHEMBL30451646 | 0.81 | S1PR3 (0.31) | S1PR3RXRARXRBRXRG | |
| SCHEMBL2912341 | 0.78 | CYP26B1 (0.37) | S1PR3ALDH1A1CYP26B1TDP1 | |
| SCHEMBL31742294 | 0.72 | HPGD (0.31) | LMNAHPGDTDP1 | |
| SCHEMBL1367336 | 0.72 | LMNA (0.61) | S1PR3RXRARXRBRXRGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250223277-A1 | COMPLEMENT FACTOR B INHIBITORS AND USES THEREOF | NOVARTIS PHARMA AG (CH) | 2025-07-10 | — | — | US | disclosed |
| WO-2013025736-A2 | DENDRON REPORTER MOLECULES | SETA BIOMEDICALS, LLC (US) | 2013-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250223277-A1 | COMPLEMENT FACTOR B INHIBITORS AND USES THEREOF | CFB, CFH, C1QBP | S1PR3 1580/4885RXRA 4562/4885RXRB 2999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.