Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12565677 | 0.83 | TAAR1 (0.49) | TAAR1HSD17B10ALDH1A1CASP1POLB | |
| SCHEMBL4598382 | 0.82 | GRM4 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4598385 | 0.75 | TAAR1 (0.40) | TAAR1HSD17B10ALDH1A1CASP1POLB | |
| SCHEMBL4824140 | 0.72 | GRM4 (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL19301621 | 0.71 | NAAA (0.52) | HSD17B10ALDH1A1 | |
| SCHEMBL14462915 | 0.71 | CTSK (0.65) | — | |
| SCHEMBL13818150 | 0.70 | TAAR1 (0.47) | TAAR1HSD17B10ALDH1A1CASP1POLB | |
| SCHEMBL4598374 | 0.68 | GRM4 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL4824953 | 0.68 | GRM4 (0.44) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL15739433 | 0.67 | NAAA (0.56) | HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013095275-A1 | NOVEL HEPATITIS C VIRUS INHIBITORS | MEDIVIR AB (SE) | 2013-06-27 | — | — | WO | disclosed |