Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1636809 | 0.82 | P2RX7 (0.55) | P2RX7 | |
| SCHEMBL2838549 | 0.82 | P2RX7 (0.55) | P2RX7 | |
| SCHEMBL1636147 | 0.73 | P2RX7 (0.50) | P2RX7 | |
| SCHEMBL1636672 | 0.73 | P2RX7 (0.50) | P2RX7 | |
| SCHEMBL1636151 | 0.65 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL1664320 | 0.64 | P2RX7 (0.33) | P2RX7 | |
| SCHEMBL1637934 | 0.62 | P2RX7 (0.51) | P2RX7 | |
| SCHEMBL2576552 | 0.61 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL2576550 | 0.61 | P2RX7 (0.46) | P2RX7 | |
| SCHEMBL21409339 | 0.61 | ATM (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932282-B2 | Imidazolidine carboxamide derivatives as P2X7 modulators | GLAXO GROUP LIMITED (GB) | 2011-04-26 | — | — | US | disclosed |