Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3325115 | 0.71 | HTT (0.39) | — | |
| SCHEMBL26098749 | 0.67 | USP30 (0.40) | — | |
| SCHEMBL15006788 | 0.67 | ALOX5 (0.41) | — | |
| SCHEMBL16836265 | 0.65 | NOS3 (0.31) | — | |
| SCHEMBL1636809 | 0.64 | P2RX7 (0.55) | P2RX7 | |
| SCHEMBL2838549 | 0.64 | P2RX7 (0.55) | P2RX7 | |
| SCHEMBL1636151 | 0.63 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL26134297 | 0.62 | LMNA (0.39) | — | |
| SCHEMBL2265666 | 0.62 | PIK3CD (0.44) | P2RX7 | |
| SCHEMBL2487318 | 0.62 | LMNA (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |