Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR2E1 | Q9Y466 | 3/20 | 0.56 |
| ▸ | RORA | P35398 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1828944 | 0.89 | NR2E1 (0.57) | NR2E1RORATRPV1 | |
| SCHEMBL16363181 | 0.81 | TRPV1 (0.54) | TRPV1S1PR1S1PR3KDM4E | |
| SCHEMBL16363169 | 0.81 | HPGD (0.52) | KMT2AMEN1KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL16363171 | 0.80 | LMNA (0.61) | KMT2AMEN1KDM4EPOLBL3MBTL1 | |
| SCHEMBL16363183 | 0.79 | S1PR1 (0.46) | TRPV1S1PR1S1PR3L3MBTL1 | |
| SCHEMBL16363186 | 0.78 | STIM1 (0.57) | TRPV1S1PR1S1PR3L3MBTL1 | |
| SCHEMBL16363163 | 0.78 | S1PR1 (0.59) | KMT2AMEN1S1PR1ALDH1A1POLB | |
| SCHEMBL16363172 | 0.77 | KCNK3 (0.47) | GAATRPV1S1PR1S1PR3ALDH1A1 | |
| SCHEMBL16363175 | 0.76 | KCNK3 (0.47) | KMT2AMEN1TRPV1S1PR1S1PR3 | |
| SCHEMBL16363156 | 0.76 | IDO1 (0.47) | KMT2AMEN1TRPV1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150005320-A9 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2015-01-01 | — | — | US | disclosed |
| US-20140107134-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | SYNTA PHARMACEUTICALS CORP. (US) | 2014-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140107134-A1 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | CXCR2, CXCL8, CCR9 | NR2E1 2068/4885RORA 107/4885CYP3A4 1068/4885 |
| US-20150005320-A9 | COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES | CXCR2, CXCL8, CCR9 | NR2E1 2068/4885RORA 107/4885CYP3A4 1068/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.