Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 10/20 | 0.35 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | TPH1 | P17752 | 1/20 | 0.30 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16079035 | 0.85 | MAPK1 (0.40) | P2RX3 | |
| SCHEMBL16363504 | 0.75 | P2RX3 (0.46) | P2RX3 | |
| SCHEMBL20655999 | 0.71 | P2RX3 (0.45) | P2RX3 | |
| SCHEMBL16058231 | 0.70 | ADORA2B (0.55) | P2RX3TLR7MEN1KMT2AADORA2B | |
| SCHEMBL17538686 | 0.69 | KDM4C (0.39) | P2RX3TLR7MEN1KMT2AKDM4C | |
| SCHEMBL20656202 | 0.69 | CNOT7 (0.50) | P2RX3MEN1KMT2A | |
| SCHEMBL20656222 | 0.68 | P2RX3 (0.34) | P2RX3 | |
| SCHEMBL19375156 | 0.68 | MAPK1 (0.47) | ADORA2B | |
| SCHEMBL18833745 | 0.67 | P2RX3 (0.38) | P2RX3MEN1KMT2AADORA2B | |
| SCHEMBL20656191 | 0.66 | CNOT7 (0.38) | P2RX3TLR7MEN1KMT2ATGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014143799-A9 | SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF | HYDRA BIOSCIENCES, INC. (US) | 2014-12-24 | — | — | WO | disclosed |