Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNOT7 | Q9UIV1 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 8/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.31 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20656028 | 0.83 | CNOT7 (0.36) | CNOT7MEN1KMT2AP2RX3TGFBR1 | |
| SCHEMBL20656222 | 0.80 | P2RX3 (0.34) | P2RX3 | |
| SCHEMBL20656202 | 0.79 | CNOT7 (0.50) | CNOT7MEN1KMT2AP2RX3 | |
| SCHEMBL16058231 | 0.71 | ADORA2B (0.55) | MEN1KMT2AP2RX3TLR7 | |
| SCHEMBL20656029 | 0.71 | P2RX3 (0.35) | P2RX3 | |
| SCHEMBL20656229 | 0.70 | P2RX3 (0.34) | P2RX3 | |
| SCHEMBL20656228 | 0.69 | MEN1 (0.32) | MEN1KMT2A | |
| SCHEMBL20656186 | 0.68 | MEN1 (0.33) | MEN1KMT2AP2RX3TGFBR1TGFBR2 | |
| SCHEMBL17538686 | 0.68 | KDM4C (0.39) | MEN1KMT2AP2RX3TLR7 | |
| SCHEMBL16364056 | 0.66 | P2RX3 (0.35) | MEN1KMT2AP2RX3TGFBR1TGFBR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019011802-A1 | NOVEL SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-01-17 | — | — | WO | disclosed |