SCHEMBL16366

SCHEMBL16366

O=C(CBr)C1CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL232996 0.97
SCHEMBL9912093 0.92 NLRP3 (0.42)
SCHEMBL21834039 0.89 LMNA (0.48)
SCHEMBL14981377 0.89 NLRP3 (0.41)
SCHEMBL32661372 0.89 NLRP3 (0.41)
SCHEMBL2624020 0.88
SCHEMBL477153 0.88
SCHEMBL1840129 0.87 NLRP3 (0.39)
SCHEMBL3218062 0.87 NLRP3 (0.39)
SCHEMBL9269248 0.86 CES2 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1069 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117105924-A Osthole 7-bit structure modified product and preparation method and application thereof 遵义医科大学 2023-11-24 CN claimed
EP-4747244-A1 MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE Redx Pharma Limited (GB) 2026-05-27 EP disclosed
US-20260138956-A1 NOVEL COMPOUNDS AND USES THEREOF RECURSION PHARMACEUTICALS INC (US) 2026-05-21 US disclosed
WO-2026107328-A1 AGONISTS OF PARATHYROID HORMONE 1 AND INCRETIN RECEPTORS SEPTERNA, INC. (US) 2026-05-21 WO disclosed
US-12617785-B2 Pyrrolo[2,3-b]pyridine-3-carboxamide compositions and methods for ameliorating hearing loss THE ROCKEFELLER UNIVERSITY (US) 2026-05-05 US disclosed
EP-4731207-A2 INHIBITORS OF HUMAN RESPIRATORY SYNCYTIAL VIRUS AND METAPNEUMOVIRUS Merck Sharp & Dohme LLC (US) 2026-04-29 EP disclosed
EP-4731627-A1 IMIDAZO[1,2-A]PYRAZIN DERIVATIVES AND THEIR USE IN THE TREATMENT OF A HELMINTH INFECTION Merck Patent GmbH (DE) 2026-04-29 EP disclosed
US-12612412-B2 Antiviral heterocyclic compounds ENANTA PHARMACEUTICALS, INC. (US) 2026-04-28 US disclosed
EP-4334298-B1 UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER SCORPION THERAPEUTICS INC (US) 2026-02-18 EP disclosed
EP-4695240-A2 CYCLIC VINYL SULFONE WRN INHIBITORS Nimbus Wadjet, Inc. (US) 2026-02-18 EP disclosed
EP-0355353-B1 Cycloalkylthiazole derivatives HOFFMANN LA ROCHE (CH) 1994-03-16 EP disclosed
EP-0563734-A1 9-fluoro-7-oxo-7H-pyrido(1,2,3-de)(1,4)benzoxazine carboxylic acids and esters and their use as antiviral agents BAYER AG (DE) 1993-10-06 EP disclosed
WO-1992022552-A1 IMIDAZO[1,5-a]QUINOXALINES THE UPJOHN COMPANY (US) 1992-12-23 WO disclosed
US-5001140-A Cycloalkylthiazoles HOFFMANN-LA ROCHE INC. (US) 1991-03-19 US disclosed
EP-0355353-A2 Cycloalkylthiazole derivatives F. HOFFMANN-LA ROCHE AG (CH) 1990-02-28 EP disclosed
EP-0227826-B1 NOVEL VITAMIN D ANALOGUES LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) 1989-10-25 EP disclosed
US-4866048-A TREATMENT OF ABNORMAL CALL POLIIFERATION OR DIFFERENTIATION LEO PHARMACEUTICAL PRODUCTS LTD. (DK) 1989-09-12 US disclosed
EP-0227826-A1 NOVEL VITAMIN D ANALOGUES. LEO PHARM PROD LTD (DK) 1987-07-08 EP disclosed
WO-1987000834-A1 NOVEL VITAMIN D ANALOGUES LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) 1987-02-12 WO disclosed
EP-0190900-A2 Cephalosporin compounds, their production, and pharmaceutical compositions containing them YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1986-08-13 EP disclosed