Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3360994 | 0.84 | GPR35 (0.44) | F2F10PLGPLAUPLAT | |
| SCHEMBL2405271 | 0.74 | MAPT (0.39) | SMN1; SMN2MAPTMITFLMNAHTT | |
| SCHEMBL12310843 | 0.73 | GPR35 (0.51) | F2F10PLGPLAUPLAT | |
| SCHEMBL2407031 | 0.65 | ADORA3 (0.33) | F2F10PLGPLAUPLAT | |
| SCHEMBL2738748 | 0.65 | S100A4 (0.47) | SMN1; SMN2MAPTMEN1KMT2AGPR35 | |
| SCHEMBL2404020 | 0.64 | MAPT (0.38) | SMN1; SMN2MAPTMITFLMNAHTT | |
| Hydrochloric Acid SCHEMBL3360037 | 0.64 | ADORA3 (0.33) | F2F10PLGPLAUPLAT | |
| SCHEMBL3363233 | 0.63 | HPGD (0.44) | SMN1; SMN2MAPTLMNAMEN1RAB9A | |
| SCHEMBL3164611 | 0.63 | MAPT (0.57) | SMN1; SMN2MAPTLMNAHTTMEN1 | |
| SCHEMBL29703894 | 0.63 | MAPT (0.57) | SMN1; SMN2MAPTLMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2236500-B1 | BICYCLO-SUBSTITUTED PYRAZOLON AZO DERIVATIVES, PREPARATION PROCESS AND PHARMACEUTICAL USE THEREOF | JIANGSU HENGRUI MEDICINE CO (CN) | 2014-12-24 | — | — | EP | disclosed |