SCHEMBL16367106

SCHEMBL16367106

CC[C@@H](C)[C@H]1C(=O)NC(=O)[C@H]1CC

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19918261 0.85 KDM4E (0.35) KDM4EALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL5617212 0.79 DAGLA (0.35) KDM4EALDH1A1
SCHEMBL20805108 0.75 MEN1 (0.35) KDM4EALDH1A1
SCHEMBL5617419 0.67 DAGLA (0.38) KDM4EALDH1A1
SCHEMBL9063676 0.67 TSHR (0.32)
SCHEMBL23048857 0.66 MEN1 (0.36) KDM4EALDH1A1CYP2C9CYP2C19
SCHEMBL16770363 0.65 PSMD14 (0.34)
SCHEMBL12800162 0.64
SCHEMBL2376039 0.64 HSD17B10 (0.39) KDM4EALDH1A1CYP3A4
SCHEMBL15259202 0.64 LMNA (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2563791-B1 A PROCESS OF A QUATERNARY AMMONIUM SALT USING PHOSPHATE SUMITOMO DAINIPPON PHARMA CO LTD (JP) 2014-12-24 EP disclosed