Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17536132 | 0.98 | HSD17B10 (0.38) | HSD17B10LMNAALDH1A1KDM4CTSHR | |
| SCHEMBL8614546 | 0.83 | ALDH1A1 (0.44) | HSD17B10LMNAALDH1A1KDM4CTSHR | |
| SCHEMBL17294176 | 0.81 | ALDH1A1 (0.43) | HSD17B10LMNAALDH1A1KDM4CTSHR | |
| SCHEMBL21292107 | 0.80 | ALDH1A1 (0.36) | HSD17B10LMNAALDH1A1KDM4CTSHR | |
| SCHEMBL21292112 | 0.78 | HSD17B10 (0.37) | HSD17B10LMNAALDH1A1KDM4CTSHR | |
| SCHEMBL6381411 | 0.77 | LMNA (0.42) | HSD17B10LMNAALDH1A1KDM4ECYP3A4 | |
| SCHEMBL642543 | 0.75 | TSHR (0.40) | HSD17B10LMNAALDH1A1KDM4CTSHR | |
| SCHEMBL4779166 | 0.75 | HSD17B10 (0.35) | HSD17B10LMNAALDH1A1KDM4CTSHR | |
| SCHEMBL6534645 | 0.74 | KDM4E (0.42) | HSD17B10LMNAALDH1A1TSHRKDM4E | |
| SCHEMBL6534635 | 0.74 | KDM4E (0.42) | HSD17B10LMNAALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853297-B2 | Method and means for infiltrating enamel lesions | CHARITE UNIVERSITATSMEDIZIN BERLIN (DE) | 2014-10-07 | — | — | US | claimed |
| US-20090304622-A1 | METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS | CHARITE-UNIVERSITATSMEDIZIN BERLIN (DE) | 2009-12-10 | — | — | US | claimed |
| WO-2020032268-A1 | SULFUR-CONTAINING POLYMERIZABLE MONOMER AND USE THEREOF | サンメディカル株式会社 | 2020-02-13 | — | — | WO | disclosed |
| US-9855195-B2 | Dental curable composition | KABUSHIKI KAISHA SHOFU (JP) | 2018-01-02 | — | — | US | disclosed |
| US-20170079890-A1 | DENTAL CURABLE COMPOSITION | KABUSHIKI KAISHA SHOFU (JP) | 2017-03-23 | — | — | US | disclosed |
| EP-2476404-B1 | Method, means and kit for infiltrating enamel lesions | CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN (DE) | 2017-03-22 | — | — | EP | disclosed |
| EP-2023884-B1 | METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS | CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN (DE) | 2017-03-22 | — | — | EP | disclosed |
| US-8853297-B2 | Method and means for infiltrating enamel lesions | CHARITE UNIVERSITATSMEDIZIN BERLIN (DE) | 2014-10-07 | — | — | US | disclosed |
| EP-2476404-A1 | Method, means and kit for infiltrating enamel lesions | Charité Universitätsmedizin Berlin (DE) | 2012-07-18 | — | — | EP | disclosed |
| US-8012958-B2 | Modulate gene expression of gamma-aminobutyric acid receptors ; antidepressants; psychological disorders; obsessive compulsive disorders ; eating disorders | Hythlam, Inc. (US) | 2011-09-06 | — | — | US | disclosed |
| US-20090304622-A1 | METHOD AND MEANS FOR INFILTRATING ENAMEL LESIONS | CHARITE-UNIVERSITATSMEDIZIN BERLIN (DE) | 2009-12-10 | — | — | US | disclosed |
| US-20080280885-A1 | Methods for Treating Anxiety Related Disorders | HYTHIAM, INC. (US) | 2008-11-13 | — | — | US | disclosed |
| US-20080255097-A1 | Methods for the Treatment of Substance Abuse and Dependence | HYTHIAM, INC. (US) | 2008-10-16 | — | — | US | disclosed |
| US-20080207601-A1 | Methods of and Compositions For the Prevention of Anxiety, Substance Abuse, and Dependence | HYTHIAM , INC. (US) | 2008-08-28 | — | — | US | disclosed |
| US-6472227-B1 | A FLUORESCEIN MOIETY IS INCLUDED IN THE TRACER, WHILE A POLY(AMINO ACID) FORMS A PART OF THE IMMUNOGEN FOR DETERMINING THE AMOUNT OF BARBITURATE IN FLUIDS, ESPECIALLY BIOLOGICAL FLUIDS SUCH AS SERUM, PLASMA OR URINE | ABBOTT LABORATORIES | 2002-10-29 | — | — | US | disclosed |
| EP-0457213-B1 | Barbiturate assay, tracers, immunogens, antibodies and kit | ABBOTT LAB (US) | 1997-07-23 | — | — | EP | disclosed |
| EP-0457213-A2 | Barbiturate assay, tracers, immunogens, antibodies and kit | ABBOTT LABORATORIES (US) | 1991-11-21 | — | — | EP | disclosed |
| EP-0373508-A2 | Barbiturate assay, tracers, immunogens and antibodies | ABBOTT LABORATORIES (US) | 1990-06-20 | — | — | EP | disclosed |